C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: pyruvate dehydrogenase kinase, isozyme 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000503176 PDK2-001 ENSG00000005882 9606 + 17:50095275-50112152 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastENST00000503176
Transcript ID Breast
ENST00000503176 0.157±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088W CIL_00088W_0001 VISTA 17:49956976-50560219

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 TAS protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004740 IDA pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0005515 IEA protein binding
GO:0005524 IDA ATP binding
GO:0005739 IEA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005967 ISS mitochondrial pyruvate dehydrogenase complex
GO:0006006 IEA glucose metabolic process
GO:0006090 TAS pyruvate metabolic process
GO:0006111 ISS regulation of gluconeogenesis
GO:0006468 IEA protein phosphorylation
GO:0006885 ISS regulation of pH
GO:0008286 ISS insulin receptor signaling pathway
GO:0010510 ISS regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010565 ISS regulation of cellular ketone metabolic process
GO:0010906 ISS regulation of glucose metabolic process
GO:0031670 ISS cellular response to nutrient
GO:0034614 IMP cellular response to reactive oxygen species
GO:0042593 ISS glucose homeostasis
GO:0042803 IPI protein homodimerization activity
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000038431 Pdk2-001 protein_coding Mus_musculus 0 1731
ENSMUST00000141712 Pdk2-003 processed_transcript Mus_musculus 0 789
ENSMUST00000155857 Pdk2-002 processed_transcript Mus_musculus 0 429
ENSMUST00000126730 Pdk2-005 processed_transcript Mus_musculus 0 235

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