C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lecithin cholesterol acyltransferase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000038896 Lcat-001 ENSMUSG00000035237 10090 - 8:105939551-105943382 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000038896
Transcript ID Adipose Adrenal Brain Breast Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000038896 1.462±0.00 1.368±0.00 3.019±3.24 0.384±0.00 0.332±0.00 275.999±200.61 0.312±0.12 2.159±0.00 5.430±6.03 0.432±0.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000030 CIL_000030_0002 CGP 8:105935728-105943382
CIL_00003H CIL_00003H_0002 CGP 8:105939551-105966115

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004607 IDA phosphatidylcholine-sterol O-acyltransferase activity
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0006644 IEA phospholipid metabolic process
GO:0006656 IEA phosphatidylcholine biosynthetic process
GO:0008203 ISO cholesterol metabolic process
GO:0030301 ISO cholesterol transport
GO:0034186 IEA apolipoprotein A-I binding
GO:0034364 IEA high-density lipoprotein particle
GO:0034372 IEA very-low-density lipoprotein particle remodeling
GO:0034375 IEA high-density lipoprotein particle remodeling
GO:0034435 IEA cholesterol esterification
GO:0042158 IDA lipoprotein biosynthetic process
GO:0042632 IEA cholesterol homeostasis
GO:0043691 IEA reverse cholesterol transport
GO:0070062 IEA extracellular vesicular exosome
GO:0090107 IDA regulation of high-density lipoprotein particle assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264005 LCAT-001 protein_coding Homo_sapiens 0 1363
ENST00000316341 SLC12A4-001 protein_coding Homo_sapiens 0 224
ENST00000422611 SLC12A4-201 protein_coding Homo_sapiens 0 224
ENST00000570980 LCAT-004 protein_coding Homo_sapiens 0 861
ENST00000573538 LCAT-007 nonsense_mediated_decay Homo_sapiens 0 488
ENST00000575277 LCAT-005 retained_intron Homo_sapiens 0 351
ENST00000575467 LCAT-003 nonsense_mediated_decay Homo_sapiens 0 745

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