C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lecithin-cholesterol acyltransferase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264005 LCAT-001 ENSG00000213398 9606 - 16:67939750-67944131 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverENST00000264005
Transcript ID Kidney Liver
ENST00000264005 28.805±0.00 40.617±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000030 CIL_000030_0001 CGP 16:67934502-67944131
CIL_00003H CIL_00003H_0001 CGP 16:67939750-67969601

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004607 IDA phosphatidylcholine-sterol O-acyltransferase activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0006629 IEA lipid metabolic process
GO:0006644 IDA phospholipid metabolic process
GO:0006656 IDA phosphatidylcholine biosynthetic process
GO:0008203 IDA cholesterol metabolic process
GO:0008374 IEA O-acyltransferase activity
GO:0030301 IDA cholesterol transport
GO:0034186 IPI apolipoprotein A-I binding
GO:0034364 IDA high-density lipoprotein particle
GO:0034372 IDA very-low-density lipoprotein particle remodeling
GO:0034375 IDA high-density lipoprotein particle remodeling
GO:0034435 IDA cholesterol esterification
GO:0042157 TAS lipoprotein metabolic process
GO:0042158 IEA lipoprotein biosynthetic process
GO:0042632 IDA cholesterol homeostasis
GO:0043691 IDA reverse cholesterol transport
GO:0044281 TAS small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0090107 IEA regulation of high-density lipoprotein particle assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000038896 Lcat-001 protein_coding Mus_musculus 0 1363

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