C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: large tumor suppressor kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000382592 LATS2-001 ENSG00000150457 9606 - 13:20973032-21061547 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000382592
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000382592 13.193±0.00 2.958±0.00 1.593±0.00 0.790±0.47 4.721±0.00 3.650±2.18 3.071±1.85 1.720±0.80 2.196±1.70 5.108±0.00 3.118±1.57 3.932±3.37 4.290±1.17 7.915±0.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003SQ CIL_0003SQ_0001 CGP 13:20777329-21061547
CIL_0003SR CIL_0003SR_0001 CGP 13:20973032-21149084

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IDA G1/S transition of mitotic cell cycle
GO:0000922 IDA spindle pole
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0006468 IDA:IEA protein phosphorylation
GO:0007067 IEA mitotic nuclear division
GO:0009755 IDA hormone-mediated signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030216 IEA keratinocyte differentiation
GO:0034613 IEA cellular protein localization
GO:0035329 IDA hippo signaling
GO:0035556 IDA intracellular signal transduction
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0046620 IEA regulation of organ growth
GO:0046872 IEA metal ion binding
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000174213 Lats2-002 nonsense_mediated_decay Mus_musculus 0 1820
ENSMUST00000022531 Lats2-001 protein_coding Mus_musculus 0 1820
ENSMUST00000173990 Lats2-003 protein_coding Mus_musculus 0 1432
ENSMUST00000174694 Lats2-004 nonsense_mediated_decay Mus_musculus 0 1310
ENSMUST00000174166 Lats2-007 protein_coding Mus_musculus 0 599
ENSDART00000081949 lats1-201 protein_coding Danio_rerio 0 560
ENSDART00000027119 lats1-001 protein_coding Danio_rerio 0 560
ENSMUST00000038381 Lats2-005 protein_coding Mus_musculus 0 475
ENSMUST00000077981 Lats2-006 protein_coding Mus_musculus 0 473
ENSMUST00000165952 Lats1-202 protein_coding Mus_musculus 0 453
ENSMUST00000040043 Lats1-201 protein_coding Mus_musculus 0 453
ENSMUST00000173964 Lats2-010 protein_coding Mus_musculus 0 283
ENSMUST00000173732 Lats2-009 protein_coding Mus_musculus 0 268
ENSDART00000109321 lats1-002 protein_coding Danio_rerio 0.000000004 69

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