C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000040250 Kmo-001 ENSMUSG00000039783 10090 + 1:175631996-175660853 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000040250
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000040250 0.730±0.28 0.862±0.14 0.023±0.00 2.980±0.35 0.298±0.16 0.160±0.04 24.589±4.08 28.956±22.12 0.945±0.27 0.087±0.12 0.282±0.13 4.520±4.30 0.193±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000L5 CIL_0000L5_0003 CGP 1:175059736-175625635
CIL_0000HM CIL_0000HM_0002 CGP 1:175600374-175662116
CIL_0000I7 CIL_0000I7_0002 CGP 1:175620381-175692776

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004502 ISS kynurenine 3-monooxygenase activity
GO:0005739 IDA mitochondrion
GO:0005741 ISS mitochondrial outer membrane
GO:0005743 IDA mitochondrial inner membrane
GO:0009651 IEA response to salt stress
GO:0016021 IEA integral component of membrane
GO:0016174 IEA NAD(P)H oxidase activity
GO:0019441 IEA tryptophan catabolic process to kynurenine
GO:0019674 ISS NAD metabolic process
GO:0019805 IEA quinolinate biosynthetic process
GO:0034354 IEA 'de novo' NAD biosynthetic process from tryptophan
GO:0043420 IEA anthranilate metabolic process
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome
GO:0070189 IEA kynurenine metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000366555 KMO-004 protein_coding Homo_sapiens 0 412
ENST00000366557 KMO-003 protein_coding Homo_sapiens 0 1046
ENST00000366558 KMO-002 protein_coding Homo_sapiens 0 1048
ENST00000366559 KMO-001 protein_coding Homo_sapiens 0 1273
ENST00000431245 KMO-009 processed_transcript Homo_sapiens 0 254

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