C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hairy/enhancer-of-split related with YRPW motif 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000042412 Hey1-201 ENSMUSG00000040289 10090 - 3:8663362-8667039 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042412
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042412 9.395±2.77 3.821±1.14 2.787±0.00 10.762±2.84 14.308±5.49 2.703±0.57 4.465±1.04 1.284±0.13 0.494±0.28 50.835±9.10 1.621±0.33 8.594±3.24 0.893±0.24 2.014±0.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002OY CIL_0002OY_0002 CGP 3:8509527-8667039
CIL_0008LP CIL_0008LP_0002 VISTA 3:8565055-9167293
CIL_0002OV CIL_0002OV_0002 CGP 3:8663362-8923918

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000988 IEA protein binding transcription factor activity
GO:0001525 IEA angiogenesis
GO:0001568 IGI blood vessel development
GO:0001570 IGI vasculogenesis
GO:0002076 IGI osteoblast development
GO:0003198 IGI epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003199 IGI endocardial cushion to mesenchymal transition involved in heart valve formation
GO:0003222 IGI ventricular trabecula myocardium morphogenesis
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007219 IEA Notch signaling pathway
GO:0009948 IGI anterior/posterior axis specification
GO:0010629 IMP negative regulation of gene expression
GO:0035939 IEA microsatellite binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045746 IEA negative regulation of Notch signaling pathway
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046983 IEA protein dimerization activity
GO:0060840 IGI artery development
GO:0071385 IEA cellular response to glucocorticoid stimulus
GO:2000678 IEA negative regulation of transcription regulatory region DNA binding
GO:2000820 IEA negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000337919 HEY1-009 protein_coding Homo_sapiens 0 1541
ENST00000354724 HEY1-001 protein_coding Homo_sapiens 0 1596
ENST00000435063 HEY1-003 processed_transcript Homo_sapiens 0 990
ENST00000518733 HEY1-006 protein_coding Homo_sapiens 0 802
ENST00000519075 HEY1-005 retained_intron Homo_sapiens 0 233
ENST00000521111 HEY1-008 retained_intron Homo_sapiens 0 418
ENST00000523531 HEY1-007 retained_intron Homo_sapiens 0 357
ENST00000523976 HEY1-004 protein_coding Homo_sapiens 0 953

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