C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hes-related family bHLH transcription factor with YRPW motif 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354724 HEY1-001 ENSG00000164683 9606 - 8:79764010-79767863 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354724
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354724 13.259±0.00 3.501±0.00 7.467±3.04 3.347±0.00 2.727±2.48 3.727±3.34 2.441±0.00 0.279±0.00 4.792±0.00 3.335±3.09 2.710±2.38 8.842±2.06 6.090±2.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002OY CIL_0002OY_0001 CGP 8:79610814-79767863
CIL_0008LP CIL_0008LP_0001 VISTA 8:79662126-80264511
CIL_0002OV CIL_0002OV_0001 CGP 8:79764010-80030289

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000983 ISS RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0000988 IDA protein binding transcription factor activity
GO:0001525 IEP angiogenesis
GO:0003184 ISS pulmonary valve morphogenesis
GO:0003190 ISS atrioventricular valve formation
GO:0003198 ISS epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003203 ISS endocardial cushion morphogenesis
GO:0003208 ISS cardiac ventricle morphogenesis
GO:0003677 IEA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA:ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0007219 IDA Notch signaling pathway
GO:0008134 NAS transcription factor binding
GO:0035912 ISS dorsal aorta morphogenesis
GO:0035939 IDA microsatellite binding
GO:0036304 ISS umbilical cord morphogenesis
GO:0045746 IDA negative regulation of Notch signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0060317 ISS cardiac epithelial to mesenchymal transition
GO:0060347 ISS heart trabecula formation
GO:0060411 ISS cardiac septum morphogenesis
GO:0060412 ISS ventricular septum morphogenesis
GO:0060716 ISS labyrinthine layer blood vessel development
GO:0060842 ISS arterial endothelial cell differentiation
GO:0061314 IC Notch signaling involved in heart development
GO:2000678 IDA negative regulation of transcription regulatory region DNA binding
GO:2000820 IDA negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
GO:2001212 ISS regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000042412 Hey1-201 protein_coding Mus_musculus 0 1596

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