C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000043735 Mthfd1l-002 ENSMUSG00000040675 10090 + 10:3973144-4156111 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043735
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043735 0.455±0.37 0.627±0.16 1.679±0.29 0.742±0.49 0.798±0.30 1.074±0.49 0.122±0.05 0.147±0.09 2.791±2.21 0.772±0.00 0.074±0.02 1.643±0.67 2.047±0.79 0.720±0.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ED CIL_0005ED_0002 CGP 10:3740364-4167081
CIL_0005EE CIL_0005EE_0002 CGP 10:3973118-4359468

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004329 IBA formate-tetrahydrofolate ligase activity
GO:0004488 IEA methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005524 IEA ATP binding
GO:0005739 ISO mitochondrion
GO:0006730 IBA one-carbon metabolic process
GO:0009257 ISO 10-formyltetrahydrofolate biosynthetic process
GO:0035999 IEA tetrahydrofolate interconversion
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000367308 MTHFD1L-008 protein_coding Homo_sapiens 0 688
ENST00000367321 MTHFD1L-003 protein_coding Homo_sapiens 0 2992
ENST00000421497 MTHFD1L-005 processed_transcript Homo_sapiens 0.00000000000003 82
ENST00000441122 MTHFD1L-004 nonsense_mediated_decay Homo_sapiens 0 573
ENST00000478643 MTHFD1L-006 processed_transcript Homo_sapiens 1e-37 159
ENST00000611279 MTHFD1L-201 protein_coding Homo_sapiens 0 2983
ENST00000618312 MTHFD1L-202 protein_coding Homo_sapiens 0 2929

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