C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040675 Mthfd1l 10090 + 10:3973118-4167081 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043735 Mthfd1l-002 3973144-4156111 protein_coding
  ENSMUST00000117291 Mthfd1l-001 3973118-4156111 protein_coding
  ENSMUST00000120585 Mthfd1l-003 3973131-4167081 protein_coding
  ENSMUST00000154517 Mthfd1l-004 4032280-4048951 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043735ENSMUST00000117291ENSMUST00000120585ENSMUST00000154517
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043735 0.455±0.37 0.627±0.16 1.679±0.29 0.742±0.49 0.798±0.30 1.074±0.49 0.122±0.05 0.147±0.09 2.791±2.21 0.772±0.00 0.074±0.02 1.643±0.67 2.047±0.79 0.720±0.33
ENSMUST00000117291 0.547±0.44 N/A 4.512±0.24 1.355±0.31 0.736±0.47 0.607±0.19 0.161±0.03 0.261±0.11 10.280±6.05 0.609±0.16 0.151±0.05 1.957±0.95 8.185±4.07 0.487±0.29
ENSMUST00000120585 0.250±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.513±0.00 N/A 0.158±0.00
ENSMUST00000154517 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.187±0.00 N/A 19.170±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ED CIL_0005ED_0002 CGP 10:3740364-4167081
CIL_0005EE CIL_0005EE_0002 CGP 10:3973118-4359468

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004329 IBA formate-tetrahydrofolate ligase activity
GO:0004488 IEA methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005524 IEA ATP binding
GO:0005739 ISO mitochondrion
GO:0006730 IBA one-carbon metabolic process
GO:0009257 ISO 10-formyltetrahydrofolate biosynthetic process
GO:0035999 IEA tetrahydrofolate interconversion
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042221 mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like protein_coding Danio_rerio
ENSG00000120254 MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like protein_coding Homo_sapiens

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