C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: beta-site APP-cleaving enzyme 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000328735 BACE2-003 ENSG00000182240 9606 + 21:41167801-41276597 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartKidneyLiverMuscleOvaryPlacentaENST00000328735
Transcript ID Colon Heart Kidney Liver Muscle Ovary Placenta
ENST00000328735 6.385±0.00 0.692±0.00 0.172±0.00 1.146±0.00 0.312±0.00 9.861±1.76 11.132±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CW CIL_0001CW_0002 CGP 21:40010999-41282518

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004190 IDA:IEA aspartic-type endopeptidase activity
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0006508 NAS:IEA proteolysis
GO:0006509 IDA membrane protein ectodomain proteolysis
GO:0016021 NAS integral component of membrane
GO:0016486 NAS peptide hormone processing
GO:0042985 IMP negative regulation of amyloid precursor protein biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000047275 Bace2-201 protein_coding Mus_musculus 0 1094

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