C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: isoprenylcysteine carboxyl methyltransferase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000343813 ICMT-001 ENSG00000116237 9606 - 1:6221193-6235940 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343813
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343813 18.055±0.00 19.852±0.00 3.662±0.00 5.722±2.48 19.937±0.00 10.838±6.26 13.408±0.00 24.462±0.00 7.306±0.00 5.971±2.27 14.503±9.35 13.954±0.00 21.334±0.57 16.834±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00019L CIL_00019L_0002 CGP 1:6181269-6221299

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0001889 IEA liver development
GO:0003880 TAS protein C-terminal carboxyl O-methyltransferase activity
GO:0004671 IEA protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0005783 IDA endoplasmic reticulum
GO:0006464 TAS cellular protein modification process
GO:0006479 IEA protein methylation
GO:0006481 IEA C-terminal protein methylation
GO:0006612 TAS protein targeting to membrane
GO:0008104 IEA protein localization
GO:0008140 IEA cAMP response element binding protein binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0035264 IEA multicellular organism growth
GO:0046578 IEA regulation of Ras protein signal transduction
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000048892 Icmt-001 protein_coding Mus_musculus 0 1162
ENSMUST00000151372 Icmt-002 nonsense_mediated_decay Mus_musculus 0 730
ENSMUST00000125617 Icmt-003 processed_transcript Mus_musculus 0 442
ENSMUST00000076183 Rnf207-010 protein_coding Mus_musculus 3e-29 135
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.0000001 64
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.0000005 62
ENSMUST00000024742 Nfkbie-201 protein_coding Mus_musculus 0.0000005 62

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