C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cAMP responsive element binding protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000049932 Creb1-004 ENSMUSG00000025958 10090 + 1:64532809-64601257 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000049932
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000049932 2.412±1.15 2.171±0.65 2.667±0.70 1.593±0.28 0.942±0.11 1.514±0.24 1.009±0.36 3.896±0.20 0.393±0.04 3.106±0.77 1.335±0.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YW CIL_0006YW_0002 CGP 1:64029447-64604548
CIL_0006YR CIL_0006YR_0002 CGP 1:64532645-64617242

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001190 IEA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005719 IEA nuclear euchromatin
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006468 ISO protein phosphorylation
GO:0007409 IMP axonogenesis
GO:0007595 IMP lactation
GO:0007613 IMP memory
GO:0007623 IDA circadian rhythm
GO:0008361 IGI regulation of cell size
GO:0010033 ISO response to organic substance
GO:0010944 IEA negative regulation of transcription by competitive promoter binding
GO:0019899 IEA enzyme binding
GO:0021983 IMP pituitary gland development
GO:0030879 IMP mammary gland development
GO:0033363 IMP secretory granule organization
GO:0033762 IMP response to glucagon
GO:0035497 IEA cAMP response element binding
GO:0040018 IMP positive regulation of multicellular organism growth
GO:0042493 IDA response to drug
GO:0043565 IDA sequence-specific DNA binding
GO:0045600 IGI positive regulation of fat cell differentiation
GO:0045672 IDA positive regulation of osteoclast differentiation
GO:0045893 IGI positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046887 IMP positive regulation of hormone secretion
GO:0046889 IGI positive regulation of lipid biosynthetic process
GO:0050821 IMP protein stabilization
GO:0060428 IMP lung epithelium development
GO:0060430 IMP lung saccule development
GO:0060509 IMP Type I pneumocyte differentiation
GO:0071294 IDA cellular response to zinc ion
GO:0071363 IDA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000353267 CREB1-002 protein_coding Homo_sapiens 0 1568
ENST00000414681 CREB1-009 protein_coding Homo_sapiens 0 370
ENST00000418081 CREB1-014 nonsense_mediated_decay Homo_sapiens 0 856
ENST00000421139 CREB1-007 protein_coding Homo_sapiens 0 396
ENST00000430624 CREB1-003 protein_coding Homo_sapiens 0 1568
ENST00000432329 CREB1-001 protein_coding Homo_sapiens 0 2049
ENST00000445803 CREB1-005 protein_coding Homo_sapiens 0 1050
ENST00000446449 CREB1-017 processed_transcript Homo_sapiens 0 202
ENST00000448277 CREB1-011 protein_coding Homo_sapiens 0 981
ENST00000452474 CREB1-006 protein_coding Homo_sapiens 0 643
ENST00000455757 CREB1-016 protein_coding Homo_sapiens 0 521
ENST00000457101 CREB1-010 protein_coding Homo_sapiens 0 628
ENST00000464407 CREB1-012 retained_intron Homo_sapiens 0 211
ENST00000480189 CREB1-013 processed_transcript Homo_sapiens 0 394
ENST00000494094 CREB1-008 retained_intron Homo_sapiens 0 416
ENST00000494983 CREB1-015 processed_transcript Homo_sapiens 0 869

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