C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cAMP responsive element binding protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000353267 CREB1-002 ENSG00000118260 9606 + 2:207529912-207603431 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000353267
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000353267 2.751±0.00 2.903±0.00 1.203±0.65 2.183±0.66 1.431±0.55 1.279±0.03 2.700±0.00 2.658±2.16 2.470±0.00 1.583±0.00 1.875±1.30 1.517±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YW CIL_0006YW_0001 CGP 2:207074137-207603431
CIL_0006YR CIL_0006YR_0001 CGP 2:207529737-207625928

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IC RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001190 IDA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003677 IEA DNA binding
GO:0003700 IEA:IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003712 TAS transcription cofactor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005719 IDA nuclear euchromatin
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006468 IDA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007219 TAS Notch signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0007623 ISS circadian rhythm
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010033 IDA response to organic substance
GO:0010944 IDA negative regulation of transcription by competitive promoter binding
GO:0016032 IEA viral process
GO:0019899 IPI enzyme binding
GO:0033762 ISS response to glucagon
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035497 IDA cAMP response element binding
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045087 TAS innate immune response
GO:0045600 ISS positive regulation of fat cell differentiation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046889 ISS positive regulation of lipid biosynthetic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050821 ISS protein stabilization
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000087366 Creb1-001 protein_coding Mus_musculus 0 2342
ENSMUST00000185594 Creb1-002 protein_coding Mus_musculus 0 1975
ENSMUST00000187811 Creb1-003 protein_coding Mus_musculus 0 1729
ENSMUST00000171164 Creb1-008 protein_coding Mus_musculus 0 1652
ENSMUST00000049932 Creb1-004 protein_coding Mus_musculus 0 1568
ENSMUST00000186335 Creb1-005 processed_transcript Mus_musculus 0 1452
ENSMUST00000190348 Creb1-007 protein_coding Mus_musculus 0 1301
ENSMUST00000190876 Creb1-006 nonsense_mediated_decay Mus_musculus 0 708
ENSMUST00000188855 Creb1-011 retained_intron Mus_musculus 0 416
ENSMUST00000179332 5730455P16Rik-201 protein_coding Mus_musculus 0.000003 60
ENSMUST00000103225 5730455P16Rik-001 protein_coding Mus_musculus 0.000003 60

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