C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NLR family, CARD domain containing 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000053085 Nlrc5-003 ENSMUSG00000074151 10090 + 8:94472763-94527272 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryENSMUST00000053085
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary
ENSMUST00000053085 4.579±1.90 1.249±0.62 2.110±0.49 0.042±0.02 8.274±1.66 0.367±0.20 0.524±0.15 0.769±0.27 1.001±0.93 2.014±0.86 0.224±0.01 0.919±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00051Y CIL_00051Y_0003 CGP 8:94472763-94570529

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0043549 IEA regulation of kinase activity
GO:0045087 IMP innate immune response
GO:0045345 IEA positive regulation of MHC class I biosynthetic process
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0051607 ISS defense response to virus
GO:0060335 ISS positive regulation of interferon-gamma-mediated signaling pathway
GO:0060339 IDA negative regulation of type I interferon-mediated signaling pathway
GO:0060340 ISS positive regulation of type I interferon-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000262510 NLRC5-001 protein_coding Homo_sapiens 0 1967
ENST00000436936 NLRC5-201 protein_coding Homo_sapiens 0 1967
ENST00000536231 NLRC5-020 retained_intron Homo_sapiens 0 357
ENST00000538110 NLRC5-006 protein_coding Homo_sapiens 0 924
ENST00000538805 NLRC5-004 protein_coding Homo_sapiens 0 1557
ENST00000539144 NLRC5-013 protein_coding Homo_sapiens 0 1469
ENST00000539881 NLRC5-003 nonsense_mediated_decay Homo_sapiens 0 946
ENST00000543030 NLRC5-008 protein_coding Homo_sapiens 0 237
ENST00000545081 NLRC5-007 nonsense_mediated_decay Homo_sapiens 0 1428

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