C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inositol 1,4,5-trisphosphate receptor, type 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000381340 ITPR2-001 ENSG00000123104 9606 - 12:26336515-26833198 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000381340
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000381340 2.034±0.00 1.385±0.00 5.576±0.00 1.715±0.71 2.956±1.15 1.735±1.28 1.264±0.50 7.912±5.86 0.907±0.09 3.134±2.10 0.100±0.00 1.462±0.78 2.013±1.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004XE CIL_0004XE_0001 CGP 12:26121991-26833198
CIL_0004XF CIL_0004XF_0001 CGP 12:26336515-26938326

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0005216 IEA ion channel activity
GO:0005220 IEA inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005262 IEA calcium channel activity
GO:0005488 IEA binding
GO:0005737 IEA cytoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005886 IDA plasma membrane
GO:0005938 IEA cell cortex
GO:0006112 TAS energy reserve metabolic process
GO:0006810 TAS transport
GO:0006811 IEA ion transport
GO:0006816 IEA calcium ion transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0015085 TAS calcium ion transmembrane transporter activity
GO:0015278 IEA calcium-release channel activity
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0030168 TAS platelet activation
GO:0031095 TAS platelet dense tubular network membrane
GO:0033017 IMP sarcoplasmic reticulum membrane
GO:0035091 IEA phosphatidylinositol binding
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043235 IDA receptor complex
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048016 IEA inositol phosphate-mediated signaling
GO:0050796 TAS regulation of insulin secretion
GO:0055085 IEA transmembrane transport
GO:0070588 IEA calcium ion transmembrane transport
GO:0071320 IEA cellular response to cAMP
GO:0071361 IEA cellular response to ethanol

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000053273 Itpr2-002 protein_coding Mus_musculus 0 8456
ENSMUST00000079573 Itpr2-001 protein_coding Mus_musculus 0 7703
ENSMUST00000139732 Itpr2-004 protein_coding Mus_musculus 0 2586
ENSMUST00000131890 Itpr2-006 protein_coding Mus_musculus 0 1851
ENSMUST00000145418 Itpr2-005 retained_intron Mus_musculus 0 1127
ENSMUST00000111673 Itpr2-003 processed_transcript Mus_musculus 0 638
ENSDART00000065092 itpr1a-201 protein_coding Danio_rerio 0 339
ENSDART00000149019 itpr1a-001 protein_coding Danio_rerio 0 339

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