C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: excision repaiross-complementing rodent repair deficiency, complementation group 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000054835 Ercc8-001 ENSMUSG00000021694 10090 + 13:108158738-108194985 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054835
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054835 2.278±0.68 1.565±0.37 1.322±0.08 5.136±0.03 2.579±0.72 2.671±0.48 1.706±0.45 2.128±0.42 2.565±1.29 3.156±1.30 1.346±0.32 3.622±1.49 2.477±1.25 10.746±4.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004LG CIL_0004LG_0002 CGP 13:108052590-108195364
CIL_0001YO CIL_0001YO_0002 CGP 13:108158731-108287105

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000109 IEA nucleotide-excision repair complex
GO:0000209 IEA protein polyubiquitination
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005634 IEA nucleus
GO:0006283 IEA transcription-coupled nucleotide-excision repair
GO:0006289 IEA nucleotide-excision repair
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0006979 IEA response to oxidative stress
GO:0009411 IMP response to UV
GO:0010165 IMP response to X-ray
GO:0016363 IEA nuclear matrix
GO:0031464 IEA Cul4A-RING E3 ubiquitin ligase complex
GO:0032403 IEA protein complex binding
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043234 IEA protein complex
GO:0045739 IEA positive regulation of DNA repair
GO:0051865 IEA protein autoubiquitination

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000265038 ERCC8-001 protein_coding Homo_sapiens 0 1301
ENST00000381118 ERCC8-003 nonsense_mediated_decay Homo_sapiens 0 1107
ENST00000439176 ERCC8-005 protein_coding Homo_sapiens 0 621
ENST00000462279 ERCC8-004 processed_transcript Homo_sapiens 0 584
ENST00000477893 ERCC8-006 retained_intron Homo_sapiens 0 488
ENST00000484330 ERCC8-007 processed_transcript Homo_sapiens 0 342
ENST00000495985 ERCC8-008 processed_transcript Homo_sapiens 0 710
ENST00000497892 ERCC8-002 retained_intron Homo_sapiens 0 689

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