C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: excision repair cross-complementation group 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000265038 ERCC8-001 ENSG00000049167 9606 - 5:60873832-60945051 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265038
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265038 0.485±0.00 0.397±0.00 0.798±0.00 1.339±0.00 0.307±0.00 1.120±0.00 1.921±0.00 0.688±0.19 0.209±0.00 0.479±0.00 1.374±0.34 2.222±0.19 3.144±0.90

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000109 IDA nucleotide-excision repair complex
GO:0000209 IDA protein polyubiquitination
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006281 TAS DNA repair
GO:0006283 IDA transcription-coupled nucleotide-excision repair
GO:0006289 IMP nucleotide-excision repair
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0006979 IDA response to oxidative stress
GO:0009411 IDA response to UV
GO:0010165 IEA response to X-ray
GO:0016363 IDA nuclear matrix
GO:0031464 IDA Cul4A-RING E3 ubiquitin ligase complex
GO:0032403 IDA protein complex binding
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043234 IDA protein complex
GO:0045739 IMP positive regulation of DNA repair
GO:0051865 IDA protein autoubiquitination

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000054835 Ercc8-001 protein_coding Mus_musculus 0 1301
ENSMUST00000123657 Ercc8-002 nonsense_mediated_decay Mus_musculus 0 994
ENSMUST00000120672 Ercc8-003 protein_coding Mus_musculus 0 689
ENSMUST00000142931 Ercc8-006 nonsense_mediated_decay Mus_musculus 0 595
ENSMUST00000152634 Ercc8-005 nonsense_mediated_decay Mus_musculus 0 529
ENSMUST00000133957 Ercc8-010 nonsense_mediated_decay Mus_musculus 0 470
ENSMUST00000129117 Ercc8-004 nonsense_mediated_decay Mus_musculus 0 470
ENSMUST00000123182 Ercc8-008 nonsense_mediated_decay Mus_musculus 0 274
ENSMUST00000123138 Ercc8-009 nonsense_mediated_decay Mus_musculus 0 267

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