C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin-1 receptor-associated kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000059286 Irak2-001 ENSMUSG00000060477 10090 + 6:113638467-113695009 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000059286
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000059286 14.744±7.16 3.835±1.45 8.739±1.64 0.502±0.00 6.792±4.25 10.600±3.48 2.284±0.63 11.145±1.29 4.171±1.13 10.042±0.69 0.822±0.31 4.406±1.77 5.627±1.83 0.475±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00061P CIL_00061P_0002 CGP 6:113623959-113695009
CIL_00061O CIL_00061O_0002 CGP 6:113638467-113711069

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001959 IEA regulation of cytokine-mediated signaling pathway
GO:0004672 ISO protein kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006468 ISO protein phosphorylation
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032088 IEA negative regulation of NF-kappaB transcription factor activity
GO:0042803 IEA protein homodimerization activity
GO:0042981 RCA regulation of apoptotic process
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0046982 IEA protein heterodimerization activity
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0070498 IEA interleukin-1-mediated signaling pathway
GO:0070555 IEA response to interleukin-1

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000256458 IRAK2-001 protein_coding Homo_sapiens 0 1107

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