C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: phosphoinositide-3-kinase adaptor protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000059672 Pik3ap1-201 ENSMUSG00000025017 10090 - 19:41274218-41385070 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000059672
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000059672 1.924±0.00 1.915±0.42 0.781±0.00 3.381±0.43 1.072±0.53 0.438±0.00 0.756±0.00 5.130±0.68 5.386±0.74 0.073±0.03 3.099±2.31 1.821±0.77 0.738±0.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005HG CIL_0005HG_0002 CGP 19:41210842-41385070
CIL_0008SO CIL_0008SO_0002 VISTA 19:41258217-41859329
CIL_0003GA CIL_0003GA_0002 CGP 19:41274218-41562246

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0014068 IMP positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IDA membrane
GO:0034122 IMP negative regulation of toll-like receptor signaling pathway
GO:0034123 IMP positive regulation of toll-like receptor signaling pathway
GO:0034134 IMP toll-like receptor 2 signaling pathway
GO:0034142 IMP toll-like receptor 4 signaling pathway
GO:0034154 IMP toll-like receptor 7 signaling pathway
GO:0034162 IMP toll-like receptor 9 signaling pathway
GO:0036312 IDA phosphatidylinositol 3-kinase regulatory subunit binding
GO:0042802 IPI identical protein binding
GO:0050727 IMP regulation of inflammatory response

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000339364 PIK3AP1-001 protein_coding Homo_sapiens 0 2248
ENST00000371110 PIK3AP1-002 protein_coding Homo_sapiens 0 2015
ENST00000468783 PIK3AP1-003 processed_transcript Homo_sapiens 0 1171

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