C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sodium channel, type IV, beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000060125 Scn4b-001 ENSMUSG00000046480 10090 + 9:45138437-45154152 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000060125
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000060125 0.246±0.02 0.242±0.09 0.544±0.03 8.392±11.77 6.044±5.10 0.070±0.02 2.524±0.11 6.643±0.24 0.089±0.10 0.389±0.17 73.216±15.76 0.150±0.04 0.025±0.01 0.030±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081E CIL_00081E_0002 VISTA 9:44577224-45180192
CIL_0003MC CIL_0003MC_0002 CGP 9:45117876-45154152
CIL_0003MB CIL_0003MB_0002 CGP 9:45138437-45204092

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001518 ISS voltage-gated sodium channel complex
GO:0005248 IDA voltage-gated sodium channel activity
GO:0005886 IEA plasma membrane
GO:0006814 IEA sodium ion transport
GO:0010765 IEA positive regulation of sodium ion transport
GO:0014704 IDA intercalated disc
GO:0017080 ISS sodium channel regulator activity
GO:0031226 ISS intrinsic component of plasma membrane
GO:0035725 IDA sodium ion transmembrane transport
GO:0044325 IEA ion channel binding
GO:0060048 IEA cardiac muscle contraction
GO:0060307 IEA regulation of ventricular cardiac muscle cell membrane repolarization
GO:0086002 IEA cardiac muscle cell action potential involved in contraction
GO:0086006 IEA voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086012 IEA membrane depolarization during cardiac muscle cell action potential
GO:0086067 IEA AV node cell to bundle of His cell communication
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:2000649 ISS regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000324727 SCN4B-001 protein_coding Homo_sapiens 0 798
ENST00000415030 SCN4B-002 retained_intron Homo_sapiens 0 630
ENST00000423160 SCN4B-003 processed_transcript Homo_sapiens 0 191
ENST00000529878 SCN4B-004 protein_coding Homo_sapiens 0 215
ENST00000532138 SCN4B-005 retained_intron Homo_sapiens 0 198

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