C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000223423 PTGS1-002 ENSG00000095303 9606 + 9:122371080-122393178 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000223423
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000223423 1.304±0.00 2.955±0.00 1.289±0.15 5.594±0.00 0.765±0.04 2.031±1.72 19.410±19.13 2.191±0.49 0.151±0.00 1.704±0.46 1.690±0.55 1.065±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NA CIL_0006NA_0001 CGP 9:122264603-122395703

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001516 ISS prostaglandin biosynthetic process
GO:0004601 TAS:IEA peroxidase activity
GO:0004666 IDA prostaglandin-endoperoxide synthase activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006629 NAS lipid metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0006954 IEA inflammatory response
GO:0006979 IEA response to oxidative stress
GO:0008217 ISS regulation of blood pressure
GO:0019369 TAS arachidonic acid metabolic process
GO:0019371 IDA cyclooxygenase pathway
GO:0020037 IEA heme binding
GO:0043231 ISS intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0051213 IEA dioxygenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000062069 Ptgs1-001 protein_coding Mus_musculus 0 1262
ENSMUST00000149930 Ptgs1-003 processed_transcript Mus_musculus 0 628
ENSMUST00000133777 Ptgs1-005 processed_transcript Mus_musculus 0 412

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