C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: aminolevulinic acid synthase 2, erythroid
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000066337 Alas2-001 ENSMUSG00000025270 10090 + X:150547375-150570638 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000066337
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000066337 3.979±0.78 0.798±0.00 5.308±4.14 3.587±0.00 1.712±0.01 66.992±49.56 6.922±1.24 201.144±214.02 22.777±8.14 2.400±0.67 34.434±13.22 5.967±2.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YC CIL_0000YC_0002 CGP X:150519519-150589868

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 ISS response to hypoxia
GO:0003870 ISS 5-aminolevulinate synthase activity
GO:0005515 IEA protein binding
GO:0005739 ISS mitochondrion
GO:0005743 ISS mitochondrial inner membrane
GO:0005759 IEA mitochondrial matrix
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0006783 IMP heme biosynthetic process
GO:0006879 IMP cellular iron ion homeostasis
GO:0030170 IEA pyridoxal phosphate binding
GO:0030218 IMP erythrocyte differentiation
GO:0042541 IMP hemoglobin biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000330807 ALAS2-006 protein_coding Homo_sapiens 0 2170
ENST00000335854 ALAS2-008 protein_coding Homo_sapiens 0 1742
ENST00000396198 ALAS2-007 protein_coding Homo_sapiens 0 1757
ENST00000455688 ALAS2-004 protein_coding Homo_sapiens 0 616
ENST00000463868 ALAS2-002 processed_transcript Homo_sapiens 0 388
ENST00000477869 ALAS2-005 processed_transcript Homo_sapiens 0 484
ENST00000493869 ALAS2-003 processed_transcript Homo_sapiens 0 388
ENST00000498636 ALAS2-001 processed_transcript Homo_sapiens 0 935

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