C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin-1 receptor-associated kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000068286 Irak1-005 ENSMUSG00000031392 10090 - X:74013926-74023915 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonOvaryTestisENSMUST00000068286
Transcript ID Adrenal Breast Colon Ovary Testis
ENSMUST00000068286 35.075±7.55 19.775±5.91 9.835±0.00 27.159±5.29 0.979±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007F4 CIL_0007F4_0002 CGP X:73942792-74023918
CIL_0007GC CIL_0007GC_0003 CGP X:74013914-74135363

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005149 IPI interleukin-1 receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005811 IDA lipid particle
GO:0016020 IDA membrane
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032494 IDA response to peptidoglycan
GO:0032496 IDA response to lipopolysaccharide
GO:0034134 IDA toll-like receptor 2 signaling pathway
GO:0034142 IDA toll-like receptor 4 signaling pathway
GO:0043406 IMP positive regulation of MAP kinase activity
GO:0043507 IMP positive regulation of JUN kinase activity
GO:0045087 IEP innate immune response
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0046777 IDA protein autophosphorylation
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0070498 IDA interleukin-1-mediated signaling pathway
GO:0090370 IMP negative regulation of cholesterol efflux

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000369973 IRAK1-004 nonsense_mediated_decay Homo_sapiens 0 647
ENST00000369974 IRAK1-001 protein_coding Homo_sapiens 0 1423
ENST00000369980 IRAK1-012 protein_coding Homo_sapiens 0 2015
ENST00000393687 IRAK1-002 protein_coding Homo_sapiens 0 1548
ENST00000429936 IRAK1-020 protein_coding Homo_sapiens 0 1349
ENST00000444230 IRAK1-017 protein_coding Homo_sapiens 0 636

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