C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, cGMP-dependent, type I
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000373980 PRKG1-002 ENSG00000185532 9606 + 10:51074174-52298350 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373980
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373980 0.432±0.00 1.577±0.00 0.244±0.00 1.450±0.41 0.442±0.00 1.168±0.23 1.291±0.46 0.349±0.00 5.285±0.00 0.830±0.00 1.583±0.00 0.477±0.13 0.605±0.40 1.517±0.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006EK CIL_0006EK_0002 CGP 10:50799409-52298350
CIL_0000ID CIL_0000ID_0001 CGP 10:50991358-52298350

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001764 IEA neuron migration
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004692 IDA:IEA cGMP-dependent protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005246 IDA calcium channel regulator activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007596 TAS blood coagulation
GO:0016358 IEA dendrite development
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019934 IEA cGMP-mediated signaling
GO:0030036 TAS actin cytoskeleton organization
GO:0030553 IEA cGMP binding
GO:0030900 IEA forebrain development
GO:0043087 IMP regulation of GTPase activity
GO:0045986 IEA negative regulation of smooth muscle contraction
GO:0060087 IEA relaxation of vascular smooth muscle
GO:0090331 IMP negative regulation of platelet aggregation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000073581 Prkg1-002 protein_coding Mus_musculus 0 3901
ENSMUST00000065067 Prkg1-001 protein_coding Mus_musculus 0 3410
ENSMUST00000182459 Prkg1-005 processed_transcript Mus_musculus 0 715
ENSMUST00000183135 Prkg1-006 processed_transcript Mus_musculus 0 715
ENSMUST00000182527 Prkg1-007 processed_transcript Mus_musculus 4e-34 152

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