C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein tyrosine phosphatase, receptor type, O
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000077115 Ptpro-201 ENSMUSG00000030223 10090 + 6:137252299-137464629 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainKidneyPlacentaTestisENSMUST00000077115
Transcript ID Bladder Brain Kidney Placenta Testis
ENSMUST00000077115 0.084±0.00 7.192±3.99 0.922±0.55 0.012±0.00 1.036±0.83

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000375 CIL_000375_0002 CGP 6:137054825-137464629
CIL_0005VB CIL_0005VB_0003 CGP 6:137252299-137654876

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000902 IMP cell morphogenesis
GO:0002548 ISS monocyte chemotaxis
GO:0003093 IMP regulation of glomerular filtration
GO:0003105 ISS negative regulation of glomerular filtration
GO:0004725 IEA:IDA protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007411 IMP axon guidance
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0016328 IDA lateral plasma membrane
GO:0017147 IDA Wnt-protein binding
GO:0030032 IMP lamellipodium assembly
GO:0032835 ISS glomerulus development
GO:0035335 IDA peptidyl-tyrosine dephosphorylation
GO:0036060 IMP slit diaphragm assembly
GO:0042803 IDA protein homodimerization activity
GO:0043197 IDA dendritic spine
GO:0070062 IEA extracellular vesicular exosome
GO:0072112 IMP glomerular visceral epithelial cell differentiation
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000281171 PTPRO-001 protein_coding Homo_sapiens 0 3197
ENST00000348962 PTPRO-002 protein_coding Homo_sapiens 0 1720
ENST00000442921 PTPRO-004 protein_coding Homo_sapiens 0 1927
ENST00000445537 PTPRO-006 protein_coding Homo_sapiens 0 1731
ENST00000538907 PTPRO-009 retained_intron Homo_sapiens 0 446
ENST00000542557 PTPRO-005 protein_coding Homo_sapiens 0 1369
ENST00000543886 PTPRO-003 protein_coding Homo_sapiens 0 893
ENST00000544244 PTPRO-007 protein_coding Homo_sapiens 0 1175

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