C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, O
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030223 Ptpro 10090 + 6:137252299-137464629 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000077115 Ptpro-201 137252299-137464629 protein_coding
  ENSMUST00000167002 Ptpro-202 137410721-137464629 protein_coding
  ENSMUST00000167679 Ptpro-203 137252299-137464629 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000077115ENSMUST00000167002ENSMUST00000167679
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000077115 N/A N/A 0.084±0.00 7.192±3.99 N/A N/A N/A 0.922±0.55 N/A N/A N/A 0.012±0.00 1.036±0.83
ENSMUST00000167002 N/A 0.577±0.14 N/A 0.916±0.00 1.519±0.10 0.478±0.22 0.367±0.09 N/A 0.087±0.05 0.116±0.03 0.610±0.32 0.083±0.04 0.174±0.03
ENSMUST00000167679 0.142±0.00 0.049±0.01 N/A N/A N/A 0.261±0.05 N/A 2.509±1.14 0.013±0.00 0.021±0.00 0.094±0.04 0.047±0.04 0.272±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000375 CIL_000375_0002 CGP 6:137054825-137464629
CIL_0005VB CIL_0005VB_0003 CGP 6:137252299-137654876

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IMP cell morphogenesis
GO:0002548 ISS monocyte chemotaxis
GO:0003093 IMP regulation of glomerular filtration
GO:0003105 ISS negative regulation of glomerular filtration
GO:0004725 IEA:IDA protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007411 IMP axon guidance
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0016328 IDA lateral plasma membrane
GO:0017147 IDA Wnt-protein binding
GO:0030032 IMP lamellipodium assembly
GO:0032835 ISS glomerulus development
GO:0035335 IDA peptidyl-tyrosine dephosphorylation
GO:0036060 IMP slit diaphragm assembly
GO:0042803 IDA protein homodimerization activity
GO:0043197 IDA dendritic spine
GO:0070062 IEA extracellular vesicular exosome
GO:0072112 IMP glomerular visceral epithelial cell differentiation
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022297 ptpro protein tyrosine phosphatase, receptor type, O protein_coding Danio_rerio
ENSG00000151490 PTPRO protein tyrosine phosphatase, receptor type, O protein_coding Homo_sapiens

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