C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein tyrosine phosphatase, receptor type, O
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000281171 PTPRO-001 ENSG00000151490 9606 + 12:15322397-15597393 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyENST00000281171
Transcript ID Brain Kidney
ENST00000281171 2.164±1.09 1.161±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000374 CIL_000374_0001 CGP 12:14973022-15348675
CIL_000375 CIL_000375_0001 CGP 12:15107783-15597399
CIL_0005VB CIL_0005VB_0002 CGP 12:15322397-15882329

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000902 ISS cell morphogenesis
GO:0002548 IMP monocyte chemotaxis
GO:0003093 ISS regulation of glomerular filtration
GO:0003105 ISS negative regulation of glomerular filtration
GO:0004725 TAS:IEA protein tyrosine phosphatase activity
GO:0005001 NAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005886 ISS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006470 ISS:IEA protein dephosphorylation
GO:0007411 ISS axon guidance
GO:0010812 ISS negative regulation of cell-substrate adhesion
GO:0010977 ISS negative regulation of neuron projection development
GO:0016021 TAS integral component of membrane
GO:0016311 IEA dephosphorylation
GO:0016324 ISS apical plasma membrane
GO:0016328 ISS lateral plasma membrane
GO:0016791 ISS:IEA phosphatase activity
GO:0017147 ISS Wnt-protein binding
GO:0030027 ISS lamellipodium
GO:0030032 ISS lamellipodium assembly
GO:0030424 ISS axon
GO:0030426 ISS growth cone
GO:0032835 IMP glomerulus development
GO:0035335 IMP peptidyl-tyrosine dephosphorylation
GO:0036060 ISS slit diaphragm assembly
GO:0042803 ISS protein homodimerization activity
GO:0043005 ISS neuron projection
GO:0043197 ISS dendritic spine
GO:0070062 IDA extracellular vesicular exosome
GO:0072112 ISS glomerular visceral epithelial cell differentiation
GO:0090090 ISS negative regulation of canonical Wnt signaling pathway
GO:0090260 ISS negative regulation of retinal ganglion cell axon guidance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000077115 Ptpro-201 protein_coding Mus_musculus 0 3197
ENSMUST00000167002 Ptpro-202 protein_coding Mus_musculus 0 1921
ENSMUST00000167679 Ptpro-203 protein_coding Mus_musculus 0 1720

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