C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: klotho
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000078856 Kl-201 ENSMUSG00000058488 10090 + 5:150952607-150993809 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000078856
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000078856 0.012±0.00 0.104±0.04 0.440±0.00 0.538±0.54 0.062±0.04 0.087±0.04 0.023±0.01 78.798±13.33 0.068±0.09 0.185±0.07 0.088±0.03 1.638±0.78 0.046±0.05 0.188±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000UY CIL_0000UY_0002 CGP 5:150673739-150993809
CIL_0000UX CIL_0000UX_0002 CGP 5:150952607-151233836

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002526 IEA acute inflammatory response
GO:0004566 IEA beta-glucuronidase activity
GO:0004871 IEA signal transducer activity
GO:0005104 IPI fibroblast growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 ISS extracellular region
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0005975 IEA carbohydrate metabolic process
GO:0006112 IMP energy reserve metabolic process
GO:0007568 IMP aging
GO:0008286 IEA insulin receptor signaling pathway
GO:0016021 ISS integral component of membrane
GO:0017134 IPI fibroblast growth factor binding
GO:0030501 IEA positive regulation of bone mineralization
GO:0055074 IGI calcium ion homeostasis
GO:0070062 IEA extracellular vesicular exosome
GO:0090080 IGI positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000114703 kl-201 protein_coding Danio_rerio 0.00000004 66
ENSDART00000149934 kl-001 protein_coding Danio_rerio 0.00000004 66
ENST00000380099 KL-001 protein_coding Homo_sapiens 0 2968
ENST00000487852 KL-002 processed_transcript Homo_sapiens 0 1799

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