C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: klotho
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000380099 KL-001 ENSG00000133116 9606 + 13:33016433-33066145 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380099
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380099 1.154±0.00 12.072±0.00 0.545±0.07 1.203±0.00 0.828±0.32 0.194±0.06 9.787±9.76 0.055±0.00 3.615±0.26 0.344±0.00 0.149±0.04 8.400±1.47 0.637±0.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000UY CIL_0000UY_0001 CGP 13:32586427-33066145
CIL_0000UX CIL_0000UX_0001 CGP 13:33016433-33350630

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002526 IEA acute inflammatory response
GO:0004553 IEA hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004566 IEA beta-glucuronidase activity
GO:0004871 IEA signal transducer activity
GO:0005104 IEA fibroblast growth factor receptor binding
GO:0005179 IEA hormone activity
GO:0005499 IEA vitamin D binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005975 IEA carbohydrate metabolic process
GO:0006112 IEA energy reserve metabolic process
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007568 IMP aging
GO:0008286 TAS insulin receptor signaling pathway
GO:0008422 TAS beta-glucosidase activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016021 TAS integral component of membrane
GO:0017134 IPI fibroblast growth factor binding
GO:0030501 IMP positive regulation of bone mineralization
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0055074 IEA calcium ion homeostasis
GO:0070062 IDA extracellular vesicular exosome
GO:0090080 IEA positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000078856 Kl-201 protein_coding Mus_musculus 0 2968
ENSDART00000114703 kl-201 protein_coding Danio_rerio 0.0000000000001 84
ENSDART00000149934 kl-001 protein_coding Danio_rerio 0.0000000000001 84

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