C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mohawk homeobox
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000079788 Mkx-001 ENSMUSG00000061013 10090 - 18:6934966-7004780 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000079788
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000079788 0.192±0.18 1.477±0.11 0.197±0.06 0.459±0.35 0.040±0.01 1.838±0.79 0.029±0.00 0.106±0.05 0.157±0.12 0.092±0.06 0.118±0.04 3.594±1.39 0.225±0.07 0.114±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00077Z CIL_00077Z_0003 CGP 18:6765205-7004780
CIL_00077Y CIL_00077Y_0003 CGP 18:6910459-7297901

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0002932 IMP tendon sheath development
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 IC transcription factor complex
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007517 IEP muscle organ development
GO:0010468 IMP regulation of gene expression
GO:0010628 IMP positive regulation of gene expression
GO:0030199 IMP collagen fibril organization
GO:0032967 IMP positive regulation of collagen biosynthetic process
GO:0035990 IMP tendon cell differentiation
GO:0035992 IMP tendon formation
GO:0043565 IEA sequence-specific DNA binding
GO:0045662 IDA negative regulation of myoblast differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000375790 MKX-001 protein_coding Homo_sapiens 0 1400
ENST00000419761 MKX-201 protein_coding Homo_sapiens 0 1393
ENST00000460919 MKX-002 protein_coding Homo_sapiens 0 928
ENST00000561227 MKX-003 protein_coding Homo_sapiens 0 195

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