C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: huntingtin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000080036 Htt-001 ENSMUSG00000029104 10090 + 5:34761744-34912534 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000080036
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000080036 4.790±2.56 5.003±3.00 3.581±0.53 8.136±1.58 1.818±0.70 3.434±1.85 1.885±0.41 2.792±1.16 2.437±1.60 5.423±0.94 1.032±0.24 5.333±1.95 3.275±1.11 6.245±2.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000748 CIL_000748_0002 CGP 5:34660379-34912534
CIL_000747 CIL_000747_0002 CGP 5:34761740-34923839

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000050 IMP urea cycle
GO:0000052 IMP citrulline metabolic process
GO:0000132 IEA establishment of mitotic spindle orientation
GO:0002039 IEA p53 binding
GO:0005515 IPI protein binding
GO:0005634 IBA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IMP mitochondrion
GO:0005770 IEA late endosome
GO:0005776 IEA autophagic vacuole
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005829 IEA cytosol
GO:0006606 IMP protein import into nucleus
GO:0006839 IMP mitochondrial transport
GO:0006888 IMP ER to Golgi vesicle-mediated transport
GO:0006890 IEA retrograde vesicle-mediated transport, Golgi to ER
GO:0006915 IMP apoptotic process
GO:0007005 IMP mitochondrion organization
GO:0007029 IMP endoplasmic reticulum organization
GO:0007030 IEA Golgi organization
GO:0007212 IMP dopamine receptor signaling pathway
GO:0007283 IMP spermatogenesis
GO:0007369 IMP gastrulation
GO:0007417 IMP central nervous system development
GO:0007420 IMP brain development
GO:0007569 IMP cell aging
GO:0007611 IMP learning or memory
GO:0007612 IMP learning
GO:0007625 IMP grooming behavior
GO:0007626 IMP locomotory behavior
GO:0008088 IMP axon cargo transport
GO:0008134 IPI transcription factor binding
GO:0008306 IMP associative learning
GO:0008340 IMP determination of adult lifespan
GO:0008542 IMP visual learning
GO:0009653 IMP anatomical structure morphogenesis
GO:0009952 IMP anterior/posterior pattern specification
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016197 IMP endosomal transport
GO:0016234 IDA inclusion body
GO:0019244 IMP lactate biosynthetic process from pyruvate
GO:0019805 IMP quinolinate biosynthetic process
GO:0021756 IMP striatum development
GO:0021988 IMP olfactory lobe development
GO:0021990 IMP neural plate formation
GO:0022008 IMP neurogenesis
GO:0030072 IMP peptide hormone secretion
GO:0030073 IMP insulin secretion
GO:0030424 IDA axon
GO:0030425 IEA dendrite
GO:0030659 IEA cytoplasmic vesicle membrane
GO:0031587 IEA positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0034047 IEA regulation of protein phosphatase type 2A activity
GO:0034452 IEA dynactin binding
GO:0035176 IMP social behavior
GO:0042445 IMP hormone metabolic process
GO:0042802 IEA identical protein binding
GO:0043066 IDA negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0044325 IEA ion channel binding
GO:0045505 IEA dynein intermediate chain binding
GO:0046902 IMP regulation of mitochondrial membrane permeability
GO:0047496 IDA vesicle transport along microtubule
GO:0048167 IMP regulation of synaptic plasticity
GO:0048341 IMP paraxial mesoderm formation
GO:0048487 IEA beta-tubulin binding
GO:0048666 IMP neuron development
GO:0050809 IMP diazepam binding
GO:0051402 IMP neuron apoptotic process
GO:0051592 IMP response to calcium ion
GO:0051881 IMP regulation of mitochondrial membrane potential
GO:0051938 IMP L-glutamate import
GO:0055072 IMP iron ion homeostasis
GO:1901215 IMP negative regulation of neuron death
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000355072 HTT-001 protein_coding Homo_sapiens 0 10080
ENST00000502820 HTT-004 processed_transcript Homo_sapiens 0 278
ENST00000506137 HTT-006 retained_intron Homo_sapiens 0 435
ENST00000508321 HTT-003 retained_intron Homo_sapiens 0 292
ENST00000509043 HTT-012 retained_intron Homo_sapiens 0 309
ENST00000509618 HTT-011 protein_coding Homo_sapiens 0 431
ENST00000510626 HTT-002 retained_intron Homo_sapiens 0 3801
ENST00000513326 HTT-005 retained_intron Homo_sapiens 0 309
ENST00000513639 HTT-008 retained_intron Homo_sapiens 0 309

Loading