C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000084027 Fgfr1-001 ENSMUSG00000031565 10090 + 8:25518792-25575714 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000084027
Transcript ID Adipose Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000084027 4.581±0.89 4.151±0.98 2.718±1.16 2.360±0.66 1.065±0.13 2.479±0.79 0.143±0.05 2.859±0.15 3.113±0.74 2.826±0.36 5.823±4.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D9 CIL_0008D9_0002 VISTA 8:25042689-25644335
CIL_0008H7 CIL_0008H7_0002 VISTA 8:25139932-25741457
CIL_0008SM CIL_0008SM_0002 VISTA 8:25140188-25742103
CIL_0008NR CIL_0008NR_0002 VISTA 8:25243011-25845762

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001525 IGI angiogenesis
GO:0001657 IGI ureteric bud development
GO:0001701 IGI in utero embryonic development
GO:0001759 IMP organ induction
GO:0002053 IGI positive regulation of mesenchymal cell proliferation
GO:0002062 IGI chondrocyte differentiation
GO:0005007 IDA fibroblast growth factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005886 ISS plasma membrane
GO:0007420 IMP brain development
GO:0007435 IMP salivary gland morphogenesis
GO:0007605 IMP sensory perception of sound
GO:0008201 ISS heparin binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0008543 IGI fibroblast growth factor receptor signaling pathway
GO:0010468 IMP regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0010863 ISS positive regulation of phospholipase C activity
GO:0010976 IGI positive regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0017134 ISS fibroblast growth factor binding
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0021769 IMP orbitofrontal cortex development
GO:0021847 IMP ventricular zone neuroblast division
GO:0030324 IMP lung development
GO:0030326 IMP embryonic limb morphogenesis
GO:0030901 IGI midbrain development
GO:0031410 IEA cytoplasmic vesicle
GO:0035607 IMP fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
GO:0042127 IMP regulation of cell proliferation
GO:0042472 IMP inner ear morphogenesis
GO:0042473 IMP outer ear morphogenesis
GO:0042474 IMP middle ear morphogenesis
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043235 ISO receptor complex
GO:0043406 ISS positive regulation of MAP kinase activity
GO:0043410 IEA positive regulation of MAPK cascade
GO:0045666 ISS positive regulation of neuron differentiation
GO:0045787 IMP positive regulation of cell cycle
GO:0046777 ISS protein autophosphorylation
GO:0048339 IGI paraxial mesoderm development
GO:0048378 IGI regulation of lateral mesodermal cell fate specification
GO:0048469 IMP cell maturation
GO:0048514 IMP blood vessel morphogenesis
GO:0048699 IMP generation of neurons
GO:0048762 IGI mesenchymal cell differentiation
GO:0060045 IGI positive regulation of cardiac muscle cell proliferation
GO:0060117 IMP auditory receptor cell development
GO:0060445 IMP branching involved in salivary gland morphogenesis
GO:0060484 IGI lung-associated mesenchyme development
GO:0060665 IDA regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0060979 TAS vasculogenesis involved in coronary vascular morphogenesis
GO:0090080 IGI positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:2001239 IMP regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000067689 fgfr1b-201 protein_coding Danio_rerio 0 1013
ENSDART00000075259 fgfr1b-202 protein_coding Danio_rerio 0 983
ENST00000326324 FGFR1-008 protein_coding Homo_sapiens 0 2699
ENST00000335922 FGFR1-003 protein_coding Homo_sapiens 0 3044
ENST00000341462 FGFR1-201 protein_coding Homo_sapiens 0 1526
ENST00000356207 FGFR1-004 protein_coding Homo_sapiens 0 2726
ENST00000397090 FGFR1-033 retained_intron Homo_sapiens 0 621
ENST00000397091 FGFR1-001 protein_coding Homo_sapiens 0 3583
ENST00000397103 FGFR1-011 protein_coding Homo_sapiens 0 1803
ENST00000397108 FGFR1-020 protein_coding Homo_sapiens 0 3232
ENST00000397113 FGFR1-012 protein_coding Homo_sapiens 0 3258
ENST00000413133 FGFR1-015 protein_coding Homo_sapiens 0 516
ENST00000425967 FGFR1-202 protein_coding Homo_sapiens 0 3258
ENST00000434187 FGFR1-016 protein_coding Homo_sapiens 0 209
ENST00000447712 FGFR1-203 protein_coding Homo_sapiens 0 3611
ENST00000466021 FGFR1-023 retained_intron Homo_sapiens 0 966
ENST00000470826 FGFR1-005 retained_intron Homo_sapiens 0 436
ENST00000474970 FGFR1-014 retained_intron Homo_sapiens 0 274
ENST00000475621 FGFR1-022 retained_intron Homo_sapiens 0 521
ENST00000484370 FGFR1-009 nonsense_mediated_decay Homo_sapiens 0 484
ENST00000487647 FGFR1-010 nonsense_mediated_decay Homo_sapiens 0 1755
ENST00000496296 FGFR1-006 retained_intron Homo_sapiens 0 532
ENST00000524528 FGFR1-032 retained_intron Homo_sapiens 0 226
ENST00000525001 FGFR1-036 protein_coding Homo_sapiens 0 1219
ENST00000526570 FGFR1-024 retained_intron Homo_sapiens 0 2627
ENST00000526742 FGFR1-038 protein_coding Homo_sapiens 0 209
ENST00000527114 FGFR1-025 retained_intron Homo_sapiens 0 1044
ENST00000527203 FGFR1-035 processed_transcript Homo_sapiens 6.99949e-42 174
ENST00000527745 FGFR1-026 retained_intron Homo_sapiens 0 643
ENST00000529552 FGFR1-037 protein_coding Homo_sapiens 0 209
ENST00000530568 FGFR1-027 protein_coding Homo_sapiens 0 209
ENST00000530701 FGFR1-029 processed_transcript Homo_sapiens 0 209
ENST00000531196 FGFR1-039 nonsense_mediated_decay Homo_sapiens 0 828
ENST00000532386 FGFR1-034 retained_intron Homo_sapiens 0 848
ENST00000532791 FGFR1-002 protein_coding Homo_sapiens 0 3554
ENST00000619564 FGFR1-204 protein_coding Homo_sapiens 0 532

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