C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000425967 FGFR1-202 ENSG00000077782 9606 - 8:38411138-38467845 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NR CIL_0008NR_0001 VISTA 8:38140056-38746180
CIL_0008SM CIL_0008SM_0001 VISTA 8:38252496-38854674
CIL_0008H7 CIL_0008H7_0001 VISTA 8:38253282-38854976
CIL_0008D9 CIL_0008D9_0001 VISTA 8:38350004-38951124

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000165 TAS MAPK cascade
GO:0001501 TAS skeletal system development
GO:0001525 IEA angiogenesis
GO:0001657 IEA ureteric bud development
GO:0001701 IEA in utero embryonic development
GO:0001759 IEA organ induction
GO:0001764 TAS neuron migration
GO:0002053 IEA positive regulation of mesenchymal cell proliferation
GO:0002062 IEA chondrocyte differentiation
GO:0004672 IEA protein kinase activity
GO:0004713 IDA:IEA protein tyrosine kinase activity
GO:0005007 IDA:IEA fibroblast growth factor-activated receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005576 NAS extracellular region
GO:0005634 IEA nucleus
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006468 NAS:IEA protein phosphorylation
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007411 TAS axon guidance
GO:0007420 IEA brain development
GO:0007435 IEA salivary gland morphogenesis
GO:0007605 IEA sensory perception of sound
GO:0008201 IDA heparin binding
GO:0008284 IMP:IEA positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 IPI:IEA fibroblast growth factor receptor signaling pathway
GO:0010468 IEA regulation of gene expression
GO:0010518 TAS positive regulation of phospholipase activity
GO:0010629 IEA negative regulation of gene expression
GO:0010863 IDA positive regulation of phospholipase C activity
GO:0010976 IEA positive regulation of neuron projection development
GO:0014068 TAS positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016021 NAS:IEA integral component of membrane
GO:0016477 TAS cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017134 IDA fibroblast growth factor binding
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0021769 IEA orbitofrontal cortex development
GO:0021847 IEA ventricular zone neuroblast division
GO:0030324 IEA lung development
GO:0030326 IEA embryonic limb morphogenesis
GO:0030901 IEA midbrain development
GO:0031410 IEA cytoplasmic vesicle
GO:0035607 IEA fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042127 IEA regulation of cell proliferation
GO:0042472 IEA inner ear morphogenesis
GO:0042473 IEA outer ear morphogenesis
GO:0042474 IEA middle ear morphogenesis
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043009 TAS chordate embryonic development
GO:0043235 IDA receptor complex
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0043410 IMP positive regulation of MAPK cascade
GO:0045087 TAS innate immune response
GO:0045595 TAS regulation of cell differentiation
GO:0045666 IMP positive regulation of neuron differentiation
GO:0045787 IEA positive regulation of cell cycle
GO:0046777 IDA protein autophosphorylation
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048339 IEA paraxial mesoderm development
GO:0048378 IEA regulation of lateral mesodermal cell fate specification
GO:0048469 IEA cell maturation
GO:0048514 IEA blood vessel morphogenesis
GO:0048699 IEA generation of neurons
GO:0048705 TAS skeletal system morphogenesis
GO:0048762 IEA mesenchymal cell differentiation
GO:0060045 IEA positive regulation of cardiac muscle cell proliferation
GO:0060117 IEA auditory receptor cell development
GO:0060445 IEA branching involved in salivary gland morphogenesis
GO:0060484 IEA lung-associated mesenchyme development
GO:0060665 IEA regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0090080 IEA positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:2001239 IEA regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000117179 Fgfr1-002 protein_coding Mus_musculus 0 3280
ENSMUST00000084027 Fgfr1-001 protein_coding Mus_musculus 0 3258
ENSMUST00000179592 Fgfr1-202 protein_coding Mus_musculus 0 3075
ENSMUST00000119398 Fgfr1-003 protein_coding Mus_musculus 0 2699
ENSMUST00000126118 Fgfr1-011 retained_intron Mus_musculus 0 2025
ENSMUST00000178276 Fgfr1-201 protein_coding Mus_musculus 0 1803
ENSMUST00000167764 Fgfr1-005 protein_coding Mus_musculus 0 1803
ENSMUST00000120106 Fgfr1-015 retained_intron Mus_musculus 0 1530
ENSDART00000067689 fgfr1b-201 protein_coding Danio_rerio 0 1007
ENSDART00000075259 fgfr1b-202 protein_coding Danio_rerio 0 981
ENSMUST00000122054 Fgfr2-004 protein_coding Mus_musculus 0 889
ENSMUST00000138104 Fgfr1-007 processed_transcript Mus_musculus 0 885
ENSMUST00000119260 Fgfr2-011 protein_coding Mus_musculus 0 856
ENSMUST00000117872 Fgfr2-002 protein_coding Mus_musculus 0 856
ENSMUST00000117073 Fgfr2-020 protein_coding Mus_musculus 0 837
ENSMUST00000117754 Fgfr2-009 protein_coding Mus_musculus 0 787
ENSMUST00000117691 Fgfr2-013 protein_coding Mus_musculus 0 682
ENSMUST00000120715 Fgfr2-010 protein_coding Mus_musculus 0 682
ENSMUST00000121064 Fgfr2-008 protein_coding Mus_musculus 0 682
ENSMUST00000120187 Fgfr2-003 protein_coding Mus_musculus 0 682
ENSMUST00000153166 Fgfr2-001 nonsense_mediated_decay Mus_musculus 0 682
ENSMUST00000121080 Fgfr2-019 protein_coding Mus_musculus 0 664
ENSMUST00000118296 Fgfr2-018 protein_coding Mus_musculus 0 664
ENSMUST00000117858 Fgfr2-014 protein_coding Mus_musculus 0 664
ENSMUST00000117357 Fgfr2-016 protein_coding Mus_musculus 0 649
ENSMUST00000120141 Fgfr2-015 protein_coding Mus_musculus 0 649
ENSMUST00000117089 Fgfr2-012 protein_coding Mus_musculus 0 649
ENSMUST00000122448 Fgfr2-017 protein_coding Mus_musculus 0 630
ENSMUST00000145218 Fgfr1-009 retained_intron Mus_musculus 0 579
ENSMUST00000124228 Fgfr1-013 protein_coding Mus_musculus 0 503
ENSDART00000125883 fgfr3-202 protein_coding Danio_rerio 0 481
ENSDART00000013534 fgfr3-201 protein_coding Danio_rerio 0 481
ENSMUST00000124096 Fgfr2-007 protein_coding Mus_musculus 0 357
ENSMUST00000129542 Fgfr2-025 retained_intron Mus_musculus 0 331
ENSMUST00000155564 Fgfr1-012 protein_coding Mus_musculus 0 289
ENSMUST00000148322 Fgfr1-014 processed_transcript Mus_musculus 0 206

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