C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: muscle, skeletal, receptor tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000084578 Musk-002 ENSMUSG00000057280 10090 + 4:58285962-58374303 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryTestisENSMUST00000084578
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Testis
ENSMUST00000084578 0.017±0.00 0.048±0.04 0.008±0.00 0.017±0.00 0.512±0.03 0.052±0.02 0.141±0.03 0.017±0.03 0.092±0.08 0.311±0.17 0.048±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016G CIL_00016G_0002 CGP 4:58042442-58374303
CIL_00016H CIL_00016H_0002 CGP 4:58285960-58553898

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0004713 ISS protein tyrosine kinase activity
GO:0004714 TAS transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 IDA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0007275 IEA multicellular organismal development
GO:0007528 IGI neuromuscular junction development
GO:0008582 IMP regulation of synaptic growth at neuromuscular junction
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030054 IEA cell junction
GO:0030154 IEA cell differentiation
GO:0030165 IPI PDZ domain binding
GO:0031594 IDA neuromuscular junction
GO:0043113 IMP receptor clustering
GO:0043235 ISO receptor complex
GO:0043525 IMP positive regulation of neuron apoptotic process
GO:0045211 IDA postsynaptic membrane
GO:0071340 IMP skeletal muscle acetylcholine-gated channel clustering
GO:2000541 IMP positive regulation of protein geranylgeranylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000189978 MUSK-201 protein_coding Homo_sapiens 0 1437
ENST00000374438 MUSK-004 protein_coding Homo_sapiens 0 399
ENST00000374439 MUSK-003 protein_coding Homo_sapiens 0 401
ENST00000374440 MUSK-202 protein_coding Homo_sapiens 0 1437
ENST00000374448 MUSK-001 protein_coding Homo_sapiens 0 3129
ENST00000416899 MUSK-002 protein_coding Homo_sapiens 0 2981

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