C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: caspase recruitment domain family, member 11
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000085786 Card11-201 ENSMUSG00000036526 10090 - 5:140872999-141000596 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000085786
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000085786 0.407±0.38 0.259±0.09 0.374±0.05 0.050±0.02 3.285±2.08 1.179±0.27 0.169±0.12 0.470±0.35 0.100±0.06 5.074±0.78 0.286±0.14 0.928±0.36 0.175±0.12 0.230±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RS CIL_0007RS_0002 VISTA 5:140361312-140964153
CIL_0002MC CIL_0002MC_0002 CGP 5:140758408-141000596
CIL_0002M9 CIL_0002M9_0002 CGP 5:140872999-142215586

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001772 IDA immunological synapse
GO:0001819 IEA positive regulation of cytokine production
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007165 IDA signal transduction
GO:0030890 IMP positive regulation of B cell proliferation
GO:0031295 ISS T cell costimulation
GO:0042101 IEA T cell receptor complex
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042981 IEA regulation of apoptotic process
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045061 IMP thymic T cell selection
GO:0045086 IMP positive regulation of interleukin-2 biosynthetic process
GO:0045121 IEA membrane raft
GO:0045577 IMP regulation of B cell differentiation
GO:0045580 IMP regulation of T cell differentiation
GO:0050700 IEA CARD domain binding
GO:0050776 IMP regulation of immune response
GO:0050870 IMP positive regulation of T cell activation
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000355508 CARD11-013 protein_coding Homo_sapiens 0 817
ENST00000356408 CARD11-012 protein_coding Homo_sapiens 0 267
ENST00000396946 CARD11-011 protein_coding Homo_sapiens 0 3917
ENST00000480332 CARD11-014 retained_intron Homo_sapiens 0 590

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