C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: chromodomain helicase DNA binding protein 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000089752 Chd8-001 ENSMUSG00000053754 10090 - 14:52198151-52237572 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089752
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089752 5.661±1.95 4.589±1.12 3.382±1.19 7.535±3.33 7.306±1.17 4.843±0.38 2.049±0.78 3.047±0.53 2.443±1.12 7.295±0.32 1.162±0.45 6.801±1.93 4.506±1.23 3.453±0.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00078L CIL_00078L_0002 CGP 14:52160419-52237791
CIL_0003JD CIL_0003JD_0002 CGP 14:52198151-52279545

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0002039 IPI p53 binding
GO:0003677 ISS DNA binding
GO:0003678 ISS DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005634 IDA nucleus
GO:0006200 IEA ATP catabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0008013 ISS beta-catenin binding
GO:0008094 ISS DNA-dependent ATPase activity
GO:0030178 ISS negative regulation of Wnt signaling pathway
GO:0032508 IEA DNA duplex unwinding
GO:0035064 ISS methylated histone binding
GO:0042393 IDA histone binding
GO:0043044 ISS ATP-dependent chromatin remodeling
GO:0043066 IMP negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0045945 ISS positive regulation of transcription from RNA polymerase III promoter
GO:0060070 ISS canonical Wnt signaling pathway
GO:0070016 IEA armadillo repeat domain binding
GO:0071339 ISS MLL1 complex
GO:2000270 IDA negative regulation of fibroblast apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000009942 chd8-201 protein_coding Danio_rerio 0 898
ENSDART00000013676 chd8-202 protein_coding Danio_rerio 0 898
ENSDART00000131837 chd8-001 protein_coding Danio_rerio 0 878
ENST00000399982 CHD8-201 protein_coding Homo_sapiens 0 10620
ENST00000430710 CHD8-001 protein_coding Homo_sapiens 0 9400
ENST00000553283 CHD8-007 protein_coding Homo_sapiens 0 313
ENST00000553622 CHD8-003 protein_coding Homo_sapiens 0 632
ENST00000553870 CHD8-012 protein_coding Homo_sapiens 0 521
ENST00000554384 CHD8-010 retained_intron Homo_sapiens 0 488
ENST00000555301 CHD8-011 retained_intron Homo_sapiens 0 695
ENST00000555935 CHD8-004 protein_coding Homo_sapiens 0 3308
ENST00000555962 CHD8-008 processed_transcript Homo_sapiens 0 929
ENST00000557329 CHD8-009 retained_intron Homo_sapiens 0 385
ENST00000557364 CHD8-002 protein_coding Homo_sapiens 0 10310
ENST00000557727 CHD8-005 retained_intron Homo_sapiens 0 1138

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