C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chromodomain helicase DNA binding protein 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053754 Chd8 10090 - 14:52198151-52237791 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089752 Chd8-001 52198151-52237572 protein_coding
  ENSMUST00000122823 Chd8-008 52212800-52214236 retained_intron
  ENSMUST00000134329 Chd8-003 52203725-52207556 retained_intron
  ENSMUST00000136528 Chd8-011 52205741-52207703 retained_intron
  ENSMUST00000140603 Chd8-009 52211848-52213379 protein_coding
  ENSMUST00000145404 Chd8-010 52207836-52213023 retained_intron
  ENSMUST00000147309 Chd8-005 52199766-52204627 retained_intron
  ENSMUST00000147827 Chd8-004 52198476-52206097 retained_intron
  ENSMUST00000149694 Chd8-006 52222599-52227597 processed_transcript
  ENSMUST00000149975 Chd8-002 52198451-52237791 protein_coding
  ENSMUST00000155614 Chd8-007 52214957-52215926 retained_intron

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089752ENSMUST00000147827ENSMUST00000149975
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089752 5.661±1.95 4.589±1.12 3.382±1.19 7.535±3.33 7.306±1.17 4.843±0.38 2.049±0.78 3.047±0.53 2.443±1.12 7.295±0.32 1.162±0.45 6.801±1.93 4.506±1.23 3.453±0.93
ENSMUST00000147827 3.296±0.99 7.997±3.46 4.597±0.88 5.745±1.15 6.034±3.16 3.607±0.54 N/A 2.626±0.92 2.149±0.52 5.576±2.23 N/A 8.130±3.48 2.769±0.28 2.472±0.15
ENSMUST00000149975 N/A N/A 3.674±1.01 5.710±4.68 N/A N/A N/A N/A 0.833±0.24 N/A 1.418±0.34 6.958±3.72 6.470±5.24 5.527±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00078L CIL_00078L_0002 CGP 14:52160419-52237791
CIL_0003JD CIL_0003JD_0002 CGP 14:52198151-52279545

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0002039 IPI p53 binding
GO:0003677 ISS DNA binding
GO:0003678 ISS DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005634 IDA nucleus
GO:0006200 IEA ATP catabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0008013 ISS beta-catenin binding
GO:0008094 ISS DNA-dependent ATPase activity
GO:0030178 ISS negative regulation of Wnt signaling pathway
GO:0032508 IEA DNA duplex unwinding
GO:0035064 ISS methylated histone binding
GO:0042393 IDA histone binding
GO:0043044 ISS ATP-dependent chromatin remodeling
GO:0043066 IMP negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0045945 ISS positive regulation of transcription from RNA polymerase III promoter
GO:0060070 ISS canonical Wnt signaling pathway
GO:0070016 IEA armadillo repeat domain binding
GO:0071339 ISS MLL1 complex
GO:2000270 IDA negative regulation of fibroblast apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075543 chd8 chromodomain helicase DNA binding protein 8 protein_coding Danio_rerio
ENSG00000100888 CHD8 chromodomain helicase DNA binding protein 8 protein_coding Homo_sapiens

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