C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: chromodomain helicase DNA binding protein 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000557364 CHD8-002 ENSG00000100888 9606 - 14:21385486-21456080 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000557364
Transcript ID Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000557364 1.261±0.00 3.207±0.00 2.416±1.42 1.711±0.00 1.650±0.00 1.500±0.99 4.046±0.00 1.392±0.44 2.561±1.18 0.949±0.21 4.418±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00078L CIL_00078L_0001 CGP 14:21351472-21456126
CIL_0003JD CIL_0003JD_0001 CGP 14:21385194-21476973

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002039 ISS p53 binding
GO:0003676 IEA nucleic acid binding
GO:0003677 IMP:IEA DNA binding
GO:0003678 IMP DNA helicase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IDA nucleus
GO:0006200 IDA ATP catabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0008013 IDA beta-catenin binding
GO:0008094 IDA DNA-dependent ATPase activity
GO:0016787 IEA hydrolase activity
GO:0016817 IEA hydrolase activity, acting on acid anhydrides
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0032508 IMP DNA duplex unwinding
GO:0035064 IDA methylated histone binding
GO:0042393 ISS histone binding
GO:0043044 IMP ATP-dependent chromatin remodeling
GO:0043234 IDA protein complex
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0045945 IMP positive regulation of transcription from RNA polymerase III promoter
GO:0060070 IDA canonical Wnt signaling pathway
GO:0071339 IDA MLL1 complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000089752 Chd8-001 protein_coding Mus_musculus 0 10310
ENSMUST00000149975 Chd8-002 protein_coding Mus_musculus 0 9084
ENSMUST00000134329 Chd8-003 retained_intron Mus_musculus 0 1432
ENSMUST00000147827 Chd8-004 retained_intron Mus_musculus 0 1170
ENSMUST00000039267 Chd7-201 protein_coding Mus_musculus 0 1044
ENSMUST00000051558 Chd7-001 protein_coding Mus_musculus 0 1044
ENSMUST00000145404 Chd8-010 retained_intron Mus_musculus 0 985
ENSMUST00000147309 Chd8-005 retained_intron Mus_musculus 0 774
ENSMUST00000140603 Chd8-009 protein_coding Mus_musculus 0 739
ENSMUST00000149694 Chd8-006 processed_transcript Mus_musculus 0 549
ENSMUST00000136528 Chd8-011 retained_intron Mus_musculus 0 420
ENSMUST00000155614 Chd8-007 retained_intron Mus_musculus 0 322
ENSMUST00000122823 Chd8-008 retained_intron Mus_musculus 0 265

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