C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: growth factor receptor bound protein 10
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000093321 Grb10-005 ENSMUSG00000020176 10090 - 11:11930508-12037401 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000093321
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000093321 30.462±7.20 19.235±5.05 10.578±0.31 43.319±7.85 12.270±2.61 3.544±1.40 12.446±1.48 7.683±2.81 60.214±68.71 14.134±2.90 4.949±1.18 16.659±6.52 33.547±23.61 4.408±0.90

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P3 CIL_0008P3_0002 VISTA 11:11375621-11977027
CIL_0008XT CIL_0008XT_0002 VISTA 11:11399170-12000205
CIL_0007SD CIL_0007SD_0002 VISTA 11:11453227-12053958
CIL_00089U CIL_00089U_0002 VISTA 11:11536402-12137998
CIL_0008KL CIL_0008KL_0002 VISTA 11:11661856-12262621
CIL_0004WV CIL_0004WV_0003 CGP 11:11814101-12038683
CIL_00072I CIL_00072I_0003 CGP 11:11930508-12464960

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001784 TAS phosphotyrosine binding
GO:0005070 IDA:IPI SH3/SH2 adaptor activity
GO:0005158 IPI insulin receptor binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0007165 TAS signal transduction
GO:0008286 IEA insulin receptor signaling pathway
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0030949 ISS positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032868 IEA response to insulin
GO:0042326 IDA negative regulation of phosphorylation
GO:0042327 IEA positive regulation of phosphorylation
GO:0045719 TAS negative regulation of glycogen biosynthetic process
GO:0046325 IMP negative regulation of glucose import
GO:0046627 IMP negative regulation of insulin receptor signaling pathway
GO:0048009 IPI insulin-like growth factor receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000309156 GRB7-001 protein_coding Homo_sapiens 0.000000000000001 90
ENST00000335866 GRB10-201 protein_coding Homo_sapiens 0 1435
ENST00000357271 GRB10-005 protein_coding Homo_sapiens 0 809
ENST00000394204 GRB7-003 protein_coding Homo_sapiens 8e-16 90
ENST00000394209 GRB7-009 protein_coding Homo_sapiens 0.000000000000001 90
ENST00000394211 GRB7-002 protein_coding Homo_sapiens 0.000000000000001 90
ENST00000398810 GRB10-202 protein_coding Homo_sapiens 0 1435
ENST00000398812 GRB10-203 protein_coding Homo_sapiens 0 1435
ENST00000401949 GRB10-003 protein_coding Homo_sapiens 0 1323
ENST00000402497 GRB10-002 protein_coding Homo_sapiens 0 1295
ENST00000402578 GRB10-006 protein_coding Homo_sapiens 0 1435
ENST00000403097 GRB10-001 protein_coding Homo_sapiens 0 1435
ENST00000406641 GRB10-004 protein_coding Homo_sapiens 0 1435
ENST00000407526 GRB10-007 protein_coding Homo_sapiens 0 1323
ENST00000428711 GRB10-015 protein_coding Homo_sapiens 0 311
ENST00000445327 GRB7-006 protein_coding Homo_sapiens 0.000000000000001 90
ENST00000473071 GRB7-007 retained_intron Homo_sapiens 0.000000000002 77
ENST00000584819 GRB7-008 retained_intron Homo_sapiens 6e-16 90

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