C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: growth factor receptor-bound protein 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000445327 GRB7-006 ENSG00000141738 9606 + 17:39738771-39747291 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverLungENST00000445327
Transcript ID Liver Lung
ENST00000445327 0.299±0.00 0.895±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00080Z CIL_00080Z_0001 VISTA 17:39318232-39918735
CIL_00098W CIL_00098W_0001 VISTA 17:39359510-39962707
CIL_0007WH CIL_0007WH_0001 VISTA 17:39374871-39978277
CIL_0002E0 CIL_0002E0_0001 CGP 17:39728496-39747291
CIL_0002PT CIL_0002PT_0001 CGP 17:39737927-39864188

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003723 IEA RNA binding
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0007165 IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0009967 TAS positive regulation of signal transduction
GO:0010494 ISS cytoplasmic stress granule
GO:0017148 ISS negative regulation of translation
GO:0019901 IDA protein kinase binding
GO:0030335 IDA positive regulation of cell migration
GO:0034063 ISS stress granule assembly
GO:0035091 IDA phosphatidylinositol binding
GO:0042802 IPI identical protein binding
GO:0042995 IEA cell projection
GO:0050900 TAS leukocyte migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000019456 Grb7-001 protein_coding Mus_musculus 0 1672
ENSMUST00000156328 Grb7-005 retained_intron Mus_musculus 0 1136
ENSMUST00000127914 Grb7-006 retained_intron Mus_musculus 0 902
ENSMUST00000133419 Grb7-004 retained_intron Mus_musculus 0 499
ENSMUST00000129034 Grb7-003 retained_intron Mus_musculus 0 368
ENSMUST00000132771 Grb7-002 protein_coding Mus_musculus 0 359
ENSMUST00000109654 Grb10-009 protein_coding Mus_musculus 0.000000000000001 90
ENSMUST00000148254 Grb10-007 processed_transcript Mus_musculus 0.000000000000001 90
ENSMUST00000093321 Grb10-005 protein_coding Mus_musculus 0.000000000000001 90

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