C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000097458 Kmo-004 ENSMUSG00000039783 10090 + 1:175632180-175662116 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainColonLungMuscleOvaryPlacentaTestisENSMUST00000097458
Transcript ID Adipose Bladder Brain Colon Lung Muscle Ovary Placenta Testis
ENSMUST00000097458 0.205±0.00 0.102±0.00 0.008±0.00 0.126±0.00 0.149±0.00 0.025±0.01 0.066±0.02 0.070±0.00 0.088±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000L5 CIL_0000L5_0003 CGP 1:175059736-175625635
CIL_0000HM CIL_0000HM_0002 CGP 1:175600374-175662116
CIL_0000I7 CIL_0000I7_0002 CGP 1:175620381-175692776

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004502 ISS kynurenine 3-monooxygenase activity
GO:0005739 IDA mitochondrion
GO:0005741 ISS mitochondrial outer membrane
GO:0005743 IDA mitochondrial inner membrane
GO:0016021 IEA integral component of membrane
GO:0019674 ISS NAD metabolic process
GO:0019805 IEA quinolinate biosynthetic process
GO:0034354 IEA 'de novo' NAD biosynthetic process from tryptophan
GO:0043420 IEA anthranilate metabolic process
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000366555 KMO-004 protein_coding Homo_sapiens 4.2039e-45 185
ENST00000366557 KMO-003 protein_coding Homo_sapiens 0 1179
ENST00000366558 KMO-002 protein_coding Homo_sapiens 0 1046
ENST00000366559 KMO-001 protein_coding Homo_sapiens 0 1046
ENST00000431245 KMO-009 processed_transcript Homo_sapiens 0 254

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