C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pleckstrin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000102881 Plek-001 ENSMUSG00000020120 10090 - 11:16971206-17008702 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102881
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102881 1.508±0.50 1.514±0.07 0.815±0.00 4.188±0.81 0.825±0.24 0.679±0.30 0.666±0.07 5.850±5.07 5.673±0.78 0.466±0.43 2.029±0.52 1.775±0.85 0.153±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008I2 CIL_0008I2_0002 VISTA 11:16884831-17492556
CIL_0003RT CIL_0003RT_0002 CGP 11:16971206-17079371

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0002576 IEA platelet degranulation
GO:0005080 IEA protein kinase C binding
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0006904 IMP vesicle docking involved in exocytosis
GO:0007229 IEA integrin-mediated signaling pathway
GO:0010572 IMP positive regulation of platelet activation
GO:0010920 IEA negative regulation of inositol phosphate biosynthetic process
GO:0010925 IEA positive regulation of inositol-polyphosphate 5-phosphatase activity
GO:0016020 IEA membrane
GO:0030030 IEA cell projection organization
GO:0030836 IMP positive regulation of actin filament depolymerization
GO:0030845 IEA phospholipase C-inhibiting G-protein coupled receptor signaling pathway
GO:0030866 IEA cortical actin cytoskeleton organization
GO:0031529 IEA ruffle organization
GO:0031532 IEA actin cytoskeleton reorganization
GO:0032233 IEA positive regulation of actin filament bundle assembly
GO:0032587 IEA ruffle membrane
GO:0033625 IMP positive regulation of integrin activation
GO:0035556 IEA intracellular signal transduction
GO:0042803 IEA protein homodimerization activity
GO:0043325 IEA phosphatidylinositol-3,4-bisphosphate binding
GO:0045744 IEA negative regulation of G-protein coupled receptor protein signaling pathway
GO:0046488 IEA phosphatidylinositol metabolic process
GO:0060305 IEA regulation of cell diameter
GO:0070493 IMP thrombin receptor signaling pathway
GO:0070527 IMP platelet aggregation
GO:0070528 IMP protein kinase C signaling
GO:0070560 IMP protein secretion by platelet

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000234313 PLEK-001 protein_coding Homo_sapiens 0 1284
ENST00000317620 PROM2-201 protein_coding Homo_sapiens 0.000002 60
ENST00000317668 PROM2-001 protein_coding Homo_sapiens 0.000002 60
ENST00000324774 CAMKK2-001 protein_coding Homo_sapiens 0.0000000007 71
ENST00000392473 CAMKK2-002 protein_coding Homo_sapiens 0.0000000007 71
ENST00000409652 APOL6-001 protein_coding Homo_sapiens 0.0000004 62
ENST00000431567 PROM2-005 nonsense_mediated_decay Homo_sapiens 0.000002 60
ENST00000474788 PLEK-002 retained_intron Homo_sapiens 0 394
ENST00000487138 PROM2-003 retained_intron Homo_sapiens 0.000002 60
ENST00000593995 FKRP-018 retained_intron Homo_sapiens 0.00007 55
ENST00000598271 FKRP-019 protein_coding Homo_sapiens 0.00007 55
ENST00000600681 FKRP-014 processed_transcript Homo_sapiens 0.00007 55
ENST00000600977 FKRP-006 processed_transcript Homo_sapiens 0.00007 55

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