C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ring finger and FYVE like domain containing protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000103218 Rffl-002 ENSMUSG00000020696 10090 - 11:82807422-82829043 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00055Q CIL_00055Q_0002 CGP 11:82764345-82804274
CIL_00055O CIL_00055O_0002 CGP 11:82781108-82871210

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002947 ISS tumor necrosis factor receptor superfamily complex
GO:0005737 ISS cytoplasm
GO:0005886 ISS plasma membrane
GO:0006511 ISS ubiquitin-dependent protein catabolic process
GO:0006886 IDA intracellular protein transport
GO:0008270 IEA zinc ion binding
GO:0010008 ISS endosome membrane
GO:0010762 IMP regulation of fibroblast migration
GO:0010804 ISS negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016874 IEA ligase activity
GO:0042787 ISS protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0061630 ISS ubiquitin protein ligase activity
GO:0070936 ISS protein K48-linked ubiquitination
GO:1901797 ISS negative regulation of signal transduction by p53 class mediator
GO:1902042 ISS negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001271 ISS negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000315249 RFFL-001 protein_coding Homo_sapiens 0 725
ENST00000394597 RFFL-004 protein_coding Homo_sapiens 0 726
ENST00000413582 RFFL-003 protein_coding Homo_sapiens 0 811
ENST00000414419 RFFL-009 protein_coding Homo_sapiens 0 593
ENST00000415395 RFFL-002 protein_coding Homo_sapiens 0 723
ENST00000447669 RFFL-005 protein_coding Homo_sapiens 0 723
ENST00000581039 RFFL-011 protein_coding Homo_sapiens 0 348
ENST00000581265 RFFL-008 nonsense_mediated_decay Homo_sapiens 0 237
ENST00000582308 RFFL-010 protein_coding Homo_sapiens 0 237
ENST00000584541 RFFL-007 processed_transcript Homo_sapiens 0 313
ENST00000584655 RFFL-006 protein_coding Homo_sapiens 0 1020
ENST00000593039 RAD51L3-RFFL-001 protein_coding Homo_sapiens 0 302

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