C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, kainate 2 (beta 2)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000105483 Grik2-002 ENSMUSG00000056073 10090 - 10:49495438-49788754 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLungMuscleOvaryENSMUST00000105483
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Lung Muscle Ovary
ENSMUST00000105483 0.206±0.00 0.309±0.27 0.081±0.07 0.092±0.01 0.118±0.02 0.067±0.02 0.089±0.04 0.010±0.00 0.164±0.10

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001662 IMP behavioral fear response
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0006874 IMP cellular calcium ion homeostasis
GO:0006886 IDA intracellular protein transport
GO:0007268 IGI synaptic transmission
GO:0008328 IC ionotropic glutamate receptor complex
GO:0014069 IDA postsynaptic density
GO:0015277 IMP kainate selective glutamate receptor activity
GO:0016020 IDA membrane
GO:0019228 IMP neuronal action potential
GO:0030425 IBA dendrite
GO:0032983 IPI kainate selective glutamate receptor complex
GO:0034220 IBA ion transmembrane transport
GO:0035235 IMP ionotropic glutamate receptor signaling pathway
GO:0035249 IMP synaptic transmission, glutamatergic
GO:0042391 IMP regulation of membrane potential
GO:0042734 IDA presynaptic membrane
GO:0043025 IDA neuronal cell body
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0045202 IDA synapse
GO:0045211 IDA postsynaptic membrane
GO:0048169 IMP regulation of long-term neuronal synaptic plasticity
GO:0048172 IMP regulation of short-term neuronal synaptic plasticity
GO:0051967 IGI negative regulation of synaptic transmission, glutamatergic
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0060080 IGI regulation of inhibitory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000318991 GRIK2-201 protein_coding Homo_sapiens 0 1109
ENST00000358361 GRIK2-008 protein_coding Homo_sapiens 0 1548
ENST00000369134 GRIK2-202 protein_coding Homo_sapiens 0 1109
ENST00000369137 GRIK2-203 protein_coding Homo_sapiens 0 1109
ENST00000369138 GRIK2-003 protein_coding Homo_sapiens 0 1550
ENST00000413795 GRIK2-002 protein_coding Homo_sapiens 0 1550
ENST00000421544 GRIK2-001 protein_coding Homo_sapiens 0 1550
ENST00000455610 GRIK2-004 protein_coding Homo_sapiens 1e-29 134

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