C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphodiesterase 4B, cAMP specific
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000106908 Pde4b-001 ENSMUSG00000028525 10090 + 4:102255003-102607259 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000106908
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000106908 4.802±0.00 0.223±0.02 10.866±2.70 9.238±0.28 1.011±0.29 7.578±0.89 0.554±0.00 0.958±0.12 12.365±0.82 13.802±2.24 0.270±0.00 0.366±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NS CIL_0002NS_0002 CGP 4:102087543-102973628

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001780 IMP neutrophil homeostasis
GO:0004115 ISS 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0008152 IEA metabolic process
GO:0030552 IEA cAMP binding
GO:0030593 IMP neutrophil chemotaxis
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0032743 IEA positive regulation of interleukin-2 production
GO:0035690 IDA cellular response to drug
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050852 IEA T cell receptor signaling pathway
GO:0050900 IMP leukocyte migration
GO:0071222 IMP cellular response to lipopolysaccharide
GO:0071944 IDA cell periphery

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000329654 PDE4B-001 protein_coding Homo_sapiens 0 2745
ENST00000341517 PDE4B-002 protein_coding Homo_sapiens 0 2745
ENST00000371045 PDE4B-007 protein_coding Homo_sapiens 0 2333
ENST00000423207 PDE4B-003 protein_coding Homo_sapiens 0 3199
ENST00000480109 PDE4B-008 protein_coding Homo_sapiens 0 1943
ENST00000483863 PDE4B-018 retained_intron Homo_sapiens 0 329
ENST00000524999 PDE4B-016 processed_transcript Homo_sapiens 0 322
ENST00000526197 PDE4B-011 protein_coding Homo_sapiens 0 638
ENST00000526666 PDE4B-013 processed_transcript Homo_sapiens 0 405
ENST00000528771 PDE4B-009 protein_coding Homo_sapiens 0 608
ENST00000531025 PDE4B-010 protein_coding Homo_sapiens 0 604
ENST00000531358 PDE4B-017 processed_transcript Homo_sapiens 0 459
ENST00000532040 PDE4B-012 processed_transcript Homo_sapiens 0 405
ENST00000534463 PDE4B-015 retained_intron Homo_sapiens 0 630

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