C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transforming growth factor, beta receptor I
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000107725 Tgfbr1-002 ENSMUSG00000007613 10090 + 4:47386216-47411035 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainTestisENSMUST00000107725
Transcript ID Brain Testis
ENSMUST00000107725 1.717±0.00 6.851±3.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007BK CIL_0007BK_0003 CGP 4:47208161-47414931
CIL_0001ZZ CIL_0001ZZ_0002 CGP 4:47353222-47474333

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IGI skeletal system development
GO:0001525 IMP angiogenesis
GO:0001701 IMP in utero embryonic development
GO:0001822 IGI kidney development
GO:0001824 IDA blastocyst development
GO:0001937 IGI negative regulation of endothelial cell proliferation
GO:0002088 IMP lens development in camera-type eye
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0005024 IDA transforming growth factor beta-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005901 ISO caveola
GO:0006468 IEA protein phosphorylation
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0007507 IMP heart development
GO:0008354 IMP germ cell migration
GO:0008584 IMP male gonad development
GO:0009791 IMP post-embryonic development
GO:0009952 IGI anterior/posterior pattern specification
GO:0010468 IMP regulation of gene expression
GO:0016021 IEA integral component of membrane
GO:0023014 IEA signal transduction by phosphorylation
GO:0030199 IMP collagen fibril organization
GO:0043066 IMP negative regulation of apoptotic process
GO:0043393 IMP regulation of protein binding
GO:0043542 IMP endothelial cell migration
GO:0045121 ISO membrane raft
GO:0048538 IMP thymus development
GO:0048663 IMP neuron fate commitment
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0048705 IGI skeletal system morphogenesis
GO:0048844 IMP artery morphogenesis
GO:0050431 IPI transforming growth factor beta binding
GO:0051491 IMP positive regulation of filopodium assembly
GO:0060017 IMP parathyroid gland development
GO:0060021 IMP palate development
GO:0060037 IMP pharyngeal system development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000374990 TGFBR1-003 protein_coding Homo_sapiens 0 1467
ENST00000374994 TGFBR1-001 protein_coding Homo_sapiens 0 1751
ENST00000549021 TGFBR1-010 protein_coding Homo_sapiens 0 289
ENST00000549766 TGFBR1-005 nonsense_mediated_decay Homo_sapiens 0 1070
ENST00000550253 TGFBR1-007 protein_coding Homo_sapiens 0 1615
ENST00000552516 TGFBR1-004 protein_coding Homo_sapiens 0 1766
ENST00000594355 CTD-2396E7.7-001 processed_pseudogene Homo_sapiens 1.99965e-42 176

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