C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: calpain 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000110721 Capn3-002 ENSMUSG00000079110 10090 + 2:120463579-120504913 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverENSMUST00000110721
Transcript ID Liver
ENSMUST00000110721 3.649±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005PL CIL_0005PL_0002 CGP 2:120355312-120461700
CIL_0004QL CIL_0004QL_0003 CGP 2:120403896-120504913
CIL_0004QM CIL_0004QM_0003 CGP 2:120456019-120563843

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001896 IDA autolysis
GO:0003824 ISS catalytic activity
GO:0004198 IDA calcium-dependent cysteine-type endopeptidase activity
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006461 IMP protein complex assembly
GO:0006508 IDA proteolysis
GO:0008233 ISS peptidase activity
GO:0008307 IMP structural constituent of muscle
GO:0014718 IDA positive regulation of satellite cell activation involved in skeletal muscle regeneration
GO:0014850 ISS response to muscle activity
GO:0030016 ISS myofibril
GO:0030018 ISS Z disc
GO:0030239 IMP myofibril assembly
GO:0030315 ISS T-tubule
GO:0031402 IDA sodium ion binding
GO:0031432 ISS titin binding
GO:0032947 IMP protein complex scaffold
GO:0033234 ISS negative regulation of protein sumoylation
GO:0043066 IMP negative regulation of apoptotic process
GO:0043122 IMP regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043234 IDA protein complex
GO:0045214 IMP sarcomere organization
GO:0045661 IDA regulation of myoblast differentiation
GO:0045862 IDA positive regulation of proteolysis
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0050790 ISS regulation of catalytic activity
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051281 IMP positive regulation of release of sequestered calcium ion into cytosol
GO:0051592 ISS response to calcium ion
GO:0055103 ISS ligase regulator activity
GO:0061061 IMP muscle structure development
GO:0070315 IDA G1 to G0 transition involved in cell differentiation
GO:0071277 IDA cellular response to calcium ion
GO:0071472 IDA cellular response to salt stress
GO:0072657 IMP protein localization to membrane
GO:0097264 ISS self proteolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000318023 CAPN3-201 protein_coding Homo_sapiens 0 2307
ENST00000337571 CAPN3-006 protein_coding Homo_sapiens 0 697
ENST00000349748 CAPN3-005 protein_coding Homo_sapiens 0 2998
ENST00000356316 CAPN3-202 protein_coding Homo_sapiens 0 697
ENST00000357568 CAPN3-008 protein_coding Homo_sapiens 0 1188
ENST00000397163 CAPN3-009 protein_coding Homo_sapiens 0 1188
ENST00000397200 CAPN3-007 protein_coding Homo_sapiens 0 697
ENST00000397204 CAPN3-012 protein_coding Homo_sapiens 0 697
ENST00000466222 CAPN3-014 retained_intron Homo_sapiens 0 697
ENST00000561817 CAPN3-013 protein_coding Homo_sapiens 0 636
ENST00000562199 CAPN3-020 processed_transcript Homo_sapiens 0 477
ENST00000564503 CAPN3-019 protein_coding Homo_sapiens 0 320
ENST00000565274 CAPN3-018 nonsense_mediated_decay Homo_sapiens 0 316
ENST00000565559 CAPN3-017 protein_coding Homo_sapiens 0 449
ENST00000567071 CAPN3-011 protein_coding Homo_sapiens 0 374
ENST00000567817 CAPN3-021 nonsense_mediated_decay Homo_sapiens 0 379
ENST00000568153 CAPN3-022 nonsense_mediated_decay Homo_sapiens 0 279
ENST00000569136 CAPN3-015 protein_coding Homo_sapiens 0 697
ENST00000569827 CAPN3-010 protein_coding Homo_sapiens 0 1014

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