C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: TYRO3 protein tyrosine kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000110783 Tyro3-001 ENSMUSG00000027298 10090 + 2:119797733-119818104 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonLiverOvaryPlacentaTestisENSMUST00000110783
Transcript ID Adrenal Colon Liver Ovary Placenta Testis
ENSMUST00000110783 0.757±0.35 1.827±0.14 0.087±0.02 5.063±2.60 0.881±0.00 0.465±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005F5 CIL_0005F5_0002 CGP 2:119763304-119818104
CIL_0005F6 CIL_0005F6_0002 CGP 2:119797733-119969581

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001779 IGI natural killer cell differentiation
GO:0004713 ISS protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005635 ISS nuclear envelope
GO:0005789 ISS endoplasmic reticulum membrane
GO:0005886 IEA plasma membrane
GO:0007283 IGI spermatogenesis
GO:0016021 IEA integral component of membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021885 IGI forebrain cell migration
GO:0030168 IMP platelet activation
GO:0032940 IMP secretion by cell
GO:0034122 IGI negative regulation of toll-like receptor signaling pathway
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0042698 IGI ovulation cycle
GO:0043277 IGI apoptotic cell clearance
GO:0043491 IGI protein kinase B signaling
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0043548 ISS phosphatidylinositol 3-kinase binding
GO:0045824 IGI negative regulation of innate immune response
GO:0046777 ISS protein autophosphorylation
GO:0046982 IPI protein heterodimerization activity
GO:0050728 IGI negative regulation of inflammatory response
GO:0051250 IGI negative regulation of lymphocyte activation
GO:0060068 IGI vagina development
GO:0070050 IMP neuron cellular homeostasis
GO:0070527 IMP platelet aggregation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000140391 tyro3-001 protein_coding Danio_rerio 9.94922e-44 183
ENSDART00000081659 tyro3-201 protein_coding Danio_rerio 3e-39 169
ENST00000263798 TYRO3-001 protein_coding Homo_sapiens 0 3400
ENST00000558165 TYRO3P-001 processed_pseudogene Homo_sapiens 0 2087
ENST00000559066 TYRO3-002 protein_coding Homo_sapiens 0 3727
ENST00000559815 TYRO3-006 nonsense_mediated_decay Homo_sapiens 0 285
ENST00000559851 TYRO3-008 nonsense_mediated_decay Homo_sapiens 0 689
ENST00000560162 TYRO3-007 retained_intron Homo_sapiens 0 688
ENST00000568343 TYRO3-010 protein_coding Homo_sapiens 0 944

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