C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eukaryotic translation initiation factor 2 alpha kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000110869 Eif2ak4-006 ENSMUSG00000005102 10090 + 2:118438842-118452290 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W0 CIL_0008W0_0002 VISTA 2:118232227-118834856
CIL_0006QT CIL_0006QT_0002 CGP 2:118277110-118475234
CIL_0006QZ CIL_0006QZ_0002 CGP 2:118388618-118479711

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004694 IDA eukaryotic translation initiation factor 2alpha kinase activity
GO:0005524 IEA ATP binding
GO:0006446 ISS regulation of translational initiation
GO:0006468 IDA protein phosphorylation
GO:0009267 IDA cellular response to starvation
GO:0017148 IGI negative regulation of translation
GO:0022626 ISS cytosolic ribosome
GO:0030968 IMP endoplasmic reticulum unfolded protein response
GO:0042803 IEA protein homodimerization activity
GO:0043558 IDA regulation of translational initiation in response to stress

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000263791 EIF2AK4-001 protein_coding Homo_sapiens 0 1000
ENST00000558629 EIF2AK4-004 retained_intron Homo_sapiens 0 830
ENST00000560855 EIF2AK4-003 protein_coding Homo_sapiens 0 1000

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