C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eukaryotic translation initiation factor 2 alpha kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263791 EIF2AK4-001 ENSG00000128829 9606 + 15:39934153-40035590 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263791
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263791 5.496±0.00 2.349±0.00 1.760±0.00 2.991±0.30 3.142±0.42 3.486±0.87 3.182±1.26 2.469±0.06 2.912±0.25 2.791±0.50 2.549±0.00 6.368±2.82 7.085±2.72 3.091±0.49

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W0 CIL_0008W0_0001 VISTA 15:39791359-40393937
CIL_0006QT CIL_0006QT_0001 CGP 15:39799023-40035591
CIL_0006QZ CIL_0006QZ_0001 CGP 15:39934146-40039188

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 ISS:IEA protein serine/threonine kinase activity
GO:0004694 ISS eukaryotic translation initiation factor 2alpha kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006446 ISS:IEA regulation of translational initiation
GO:0006468 ISS:IEA protein phosphorylation
GO:0009267 IEA cellular response to starvation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017148 IEA negative regulation of translation
GO:0022626 ISS cytosolic ribosome
GO:0030968 IEA endoplasmic reticulum unfolded protein response
GO:0042803 IEA protein homodimerization activity
GO:0043558 IEA regulation of translational initiation in response to stress

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005233 Eif2ak4-001 protein_coding Mus_musculus 0 5579
ENSMUST00000110874 Eif2ak4-002 protein_coding Mus_musculus 0 5289
ENSMUST00000102527 Eif2ak4-201 protein_coding Mus_musculus 0 5175
ENSMUST00000110872 Eif2ak4-003 protein_coding Mus_musculus 0 5175
ENSMUST00000110870 Eif2ak4-004 protein_coding Mus_musculus 0 4868
ENSMUST00000110877 Eif2ak4-005 protein_coding Mus_musculus 0 1929
ENSMUST00000110869 Eif2ak4-006 protein_coding Mus_musculus 0 1000
ENSMUST00000125281 Eif2ak4-007 processed_transcript Mus_musculus 0 381
ENSMUST00000153820 Pml-003 protein_coding Mus_musculus 0.00000005 66
ENSMUST00000181377 Slc35a5-004 retained_intron Mus_musculus 0.0000002 64
ENSMUST00000141278 Lypla1-004 retained_intron Mus_musculus 0.000002 60
ENSMUST00000044297 Igfbpl1-001 protein_coding Mus_musculus 0.00003 57
ENSMUST00000094805 Ccdc8-001 protein_coding Mus_musculus 0.0001 55
ENSMUST00000127431 Cpne7-004 retained_intron Mus_musculus 0.0004 53
ENSMUST00000035519 Otud7b-201 protein_coding Mus_musculus 0.0004 53
ENSMUST00000098849 Otud7b-002 protein_coding Mus_musculus 0.0004 53
ENSMUST00000090785 Otud7b-001 protein_coding Mus_musculus 0.0004 53

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